ArticleBMC geriatrics2022
Effects of cognitive ageing trajectories on multiple adverse outcomes among Chinese community-dwelling elderly population.
Article in BMC geriatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 11 citations in OpenAlex.
- Multi-trajectory patterns of ADL, cognition, and depression with fall risk: evidence from a longitudinal study in China.BMC geriatrics · 2026Article
- Cognitive trajectories in older adults and associated mortality and predictors.Social psychiatry and psychiatric epidemiology · 2025Article
- Association between social capital and trajectories of cognitive function among Chinese older adults.BMC public health · 2025Article
- Risk and protective factors for cognitive decline in Brazilian lower educated older adults: A 15-year follow-up study using group-based trajectory modelling.Archives of gerontology and geriatrics · 2024Article
- Association Between Cognitive Trajectories and Subsequent Health Status, Depressive Symptoms, and Mortality Among Older Adults in the United States: Findings From a Nationally Representative Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Article
- Longitudinal association of adverse childhood experiences with cognitive function trajectories among middle-aged and older adults: group-based trajectory modeling.Frontiers in psychiatry · 2024Article
- Can the Frailty of Older Adults in China Change? Evidence from a Random-Intercept Latent Transition Profile Analysis.Behavioral sciences (Basel, Switzerland) · 2023Article
- Turning Point of Cognitive Decline for Chinese Older Adults from a Longitudinal Analysis: Protective Factors and Risk Factors.Healthcare (Basel, Switzerland) · 2022Article
- Reading Holy Quran Associated With Better Cognitive Function in Older Adults: A Systematic Review.Gerontology & geriatric medicineReview
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWhether cognitive ageing trajectory is related to common functional deficits independent of initial cognitive function remains inconclusive. We aimed to explore the adverse health effect and potential predictive factors of distinct cognitive trajectories among Chinese older adults.
methodsThree thousand five hundred eighty-one community-dwelling older adults who completed three consecutive cognitive function examinations with the Mini-Mental State Examination (MMSE) over 5 years and were without cognitive impairment at enrollment were included. A group-based trajectory model was used to estimate cognitive ageing trajectories. Multivariable-adjusted odds ratio (OR) and 95% confidence intervals (CI) were computed with logistic regression models to identify potential baseline determinants and health effect of cognitive trajectories on various adverse outcomes.
resultsTwo distinct cognitive ageing trajectories were identified with about 5.3% of the study participants ascribed to the rapidly decreasing group. Subjects with rapidly decreasing cognition showed significantly higher odds (OR, 95%CI) of experiencing frailty (4.04, 2.77-5.86), falls (2.01, 1.05-3.70), balance impairment (4.20, 2.75-6.38), high fall risk (5.66, 2.67-11.77) based on the Tinetti total score, disability in activities of daily living (1.76, 1.19-2.56), disability in instrumental activities of daily living (1.52, 1.05-2.19), and motor cognitive risk syndrome (2.24, 1.23-3.98) compared with their steadily decreasing counterparts. Individuals with older age, low education level, no marriage, high score of rapid eye movement behavior disorders, poor physical and cognitive function at baseline were more predisposed to an accelerated cognitive decline.
conclusionsFaster cognitive decline was independently associated with higher risk of multiple adverse events. Our findings put more emphasis on a routine and constant surveillance of cognitive function among community-dwelling older adults.
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