Evidence map›Paper›PMID 35995839›Full record

ArticleScientific reports2022

Relationship between lipid accumulation product and oxidative biomarkers by gender in adults from Yucatan, Mexico.

Roberto Lugo, Azalia Avila-Nava, Alfredo Geovanny Pech-Aguilar, Isabel Medina-Vera, Martha Guevara-Cruz, Ana Ligia Gutiérrez Solis

Abstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Roberto Lugo *Hospital Regional de Alta Especialidad de la Península de Yucatán (HRAEPY), Calle 7, No. 433 por 20 y 22, Fraccionamiento Altabrisa, 97130, Mérida, Yucatán, Mexico.ORCID 0000-0001-6353-9060
Azalia Avila-Nava *Hospital Regional de Alta Especialidad de la Península de Yucatán (HRAEPY), Calle 7, No. 433 por 20 y 22, Fraccionamiento Altabrisa, 97130, Mérida, Yucatán, Mexico.ORCID 0000-0003-3363-1477
Alfredo Geovanny Pech-AguilarHospital Regional de Alta Especialidad de la Península de Yucatán (HRAEPY), Calle 7, No. 433 por 20 y 22, Fraccionamiento Altabrisa, 97130, Mérida, Yucatán, Mexico.ORCID 0000-0001-7321-1501
Isabel Medina-VeraDepartamento de Metodología de la Investigación, Instituto Nacional de Pediatría (INP), 04530, Mexico City, Mexico.ORCID 0000-0003-4027-2329
Martha Guevara-CruzDepartamento de Fisiología de la Nutrición, Instituto Nacional de Nutrición y Ciencias Médicas Salvador Zubirán (INCMNSZ), 14080, Mexico City, Mexico.ORCID 0000-0002-8996-3481
Ana Ligia Gutiérrez SolisHospital Regional de Alta Especialidad de la Península de Yucatán (HRAEPY), Calle 7, No. 433 por 20 y 22, Fraccionamiento Altabrisa, 97130, Mérida, Yucatán, Mexico. ganaligia@gmail.com.ORCID 0000-0002-4302-4753

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Excessive adipose tissue can lead to metabolic abnormalities resulting in lipid alteration and oxidative stress (OS) status. The lipid accumulation product (LAP) index is a biomarker that indicates central lipid accumulation and has been proposed as an accurate and independent indicator of risk for several cardiometabolic related conditions. There is a lack of information about the possible association of LAP and OS biomarkers. Therefore, this work aimed to investigate the relationship between LAP and OS biomarkers in adults. A cross-sectional study was performed in 250 subjects attending the Hospital Regional de Alta Especialidad de la Península de Yucatán. Anthropometrical and clinical parameters were measured. The serum oxidative biomarkers such as malondialdehyde (MDA) and total antioxidant capacity (TAC) were evaluated by spectrophotometry and by the oxygen radical absorbance capacity (ORAC), respectively. A positive and significant correlation between serum levels of MDA and LAP (r = 0.162, p = 0.010) was observed. This relationship was stronger in women (r = 0.189, p = 0.013) than in men. The association between them remained significant after adjusting for confounders (r = 0.23, p < 0.001). A cutoff of LAP of 73.73 predicts high levels of MDA in women aged between 40 and 59. LAP index was associated with OS biomarkers in women and men from Yucatan, Mexico. Therefore, the elevation of the LAP index could identify an imbalance in the redox status.

Indexed as

Lipid Accumulation ProductAdultBiomarkersCross-Sectional StudiesFemaleHumansLipidsMaleMexicoMiddle AgedOxidation-ReductionOxidative StressBiomarkersLipids

Identifiers

PMID35995839
PMCPMC9395434

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.