ArticleNature communications2022
Population-based tract-to-region connectome of the human brain and its hierarchical topology.
Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 108 papers, 1 of them a synthesis that pooled it.
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Who cites it
108 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Literature Review on Lesion-Symptom Mapping and Deep Brain Stimulation for Poststroke Spasticity: Restoring a Dysfunctional Network?Stereotactic and functional neurosurgery · 2025Pooled it
- Reproducibility of diffusion, shape, and connectivity metrics across scanners: Implications for multi-site tractography.NeuroImage · 2026Article
- Patient-specific structural connectomic differences of deep brain stimulation targets in treatment-resistant obsessive-compulsive disorder patients.Translational psychiatry · 2026Observational
- White matter and impulsivity are prospectively associated with non‑suicidal self‑injury in youth: evidence for sex differences.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Multi-modal lesion mapping of expressive aprosodia.Cortex; a journal devoted to the study of the nervous system and behavior · 2026Article
- Assessing subcortical, brainstem and cerebellar metabolic patterns using [18F]FDG PET-CT imaging in dementia with Lewy bodies.European journal of nuclear medicine and molecular imaging · 2026Article
- Anatomical white matter tracts span the cortical hierarchy to support cognitive diversity.Nature human behaviour · 2026Article
- Article
- Restriction-Weighted Q-Space Trajectory Imaging (ResQ): Toward Mapping Diffusion-Time Effects With Tensor-Valued Diffusion Encoding in Human Prostate Cancer Xenografts.NMR in biomedicine · 2026Article
- Cognition disconnected: the influence of domain-general cognition (g) in lesion-deficit mapping.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- A longitudinal resource for mapping interindividual variation in the aging connectome.Scientific data · 2026Article
- Cerebellar Tracts Microstructural Characteristics and Severity of Language Impairment in Post-stroke Patients with Aphasia: A DTI Study.Cerebellum (London, England) · 2026Article
- Reduced integrity in the frontal aslant tract's premotor connections is associated with dysfluency severity in stuttering.PNAS nexus · 2026Article
- Clinically Feasible White Matter Fiber Tractography in Peritumoral Zones With Cerebral Vasogenic Edema.Magnetic resonance in medicine · 2026Article
- Disrupted integration-segregation balance in the intact hemisphere in chronic spatial neglect.Brain structure & function · 2026Article
- Microglia Pyroptosis-Derived IL-18 Drives White Matter Injury in Developing Brain following Hypothermic Hypoxia-Ischemia.Neuroscience bulletin · 2026Article
- Structural connectome changes as biomarkers of stroke recovery: a longitudinal 7T MRI study.BMC neuroscience · 2026Article
- SPECTRA: Spatial Inference for Tractometry Toward Precision Mapping of White Matter Microstructure.bioRxiv : the preprint server for biology · 2026Article
- White matter reflects the childhood exposome.bioRxiv : the preprint server for biology · 2026Article
- The nature and interpretation of BOLD signals in white matter - A review.Magnetic resonance imaging · 2026Review
48 more citing papers are in PubMed but not listed here.
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1 author.
Funding
Abstract
Connectome maps region-to-region connectivities but does not inform which white matter pathways form the connections. Here we constructed a population-based tract-to-region connectome to fill this information gap. The constructed connectome quantifies the population probability of a white matter tract innervating a cortical region. The results show that ~85% of the tract-to-region connectome entries are consistent across individuals, whereas the remaining (~15%) have substantial individual differences requiring individualized mapping. Further hierarchical clustering on cortical regions revealed dorsal, ventral, and limbic networks based on the tract-to-region connective patterns. The clustering results on white matter bundles revealed the categorization of fiber bundle systems in the association pathways. This tract-to-region connectome provides insights into the connective topology between cortical regions and white matter bundles. The derived hierarchical relation further offers a categorization of gray and white matter structures.
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