ArticleGastroenterology2022
Comparison of Anorectal Manometry, Rectal Balloon Expulsion Test, and Defecography for Diagnosing Defecatory Disorders.
Article in Gastroenterology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 49 citations in OpenAlex.
- High-resolution anorectal manometry in chronic constipation-Defining dysfunction beyond diagnosis.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026Article
- Rome V Criteria for Adults: What's New and Why?United European gastroenterology journal · 2026Review
- Diagnostic Value of the Anal Endoluminal Functional Luminal Imaging Probe for the Diagnosis of Anismus: An Exploratory Study.Neurogastroenterology and motility · 2026Article
- Sensation of Incomplete Evacuation in Patients With Fecal Incontinence: A Cross-Sectional Study of a Tertiary Referral Cohort.Neurogastroenterology and motility · 2026Article
- Diagnostic Accuracy of Anorectal Manometry in Identifying Dyssynergic Defecation among Chronic Constipation Patients.Annals of African medicine · 2026Observational
- Dyssynergia phenotypes in obstructed defecation: insights from Fecobionics assessment.BMJ open gastroenterology · 2026Observational
- Bali Chronic Constipation Roundtable Report: Chronic Constipation Management in Asia.Journal of neurogastroenterology and motility · 2026Article
- Multicenter Validation of Video-based Deep Learning to Evaluate Defecation Patterns on 3-dimensional High-definition Anorectal Manometry.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2026Article
- Burst-patterned stimulation restores colonic motility in preclinical models.Science translational medicine · 2025Article
- Inadequate Propulsion and Pelvic Floor Relaxation in Dyssynergic Defecation: Insights From Synchronous Proctomanometry.Gastroenterology · 2025Article
- Clinical relevance of transperineal ultrasound compared with anorectal manometry for the evaluation of female patients with obstructive defecation syndrome.BMC gastroenterology · 2025Article
- Validation of the London Classification for Rectal Hyposensitivity in an Anorectal Manometry Database of 2540 Patients With Functional Defecatory Disorder.Journal of neurogastroenterology and motility · 2025Article
- Overall and Regional Colonic Transit Abnormalities in Elderly Patients with Constipation.Digestive diseases and sciences · 2025Article
- Can Digital Rectal Examination Identify the Subtype of Dyssynergic Disorders as Well as High Resolution Anorectal Manometry?JGH open : an open access journal of gastroenterology and hepatology · 2025Article
- High-Resolution Anorectal Manometry and Balloon Expulsion Test Outcomes in Functional Constipation: A Comparative Study.Medical science monitor : international medical journal of experimental and clinical research · 2024Article
- Defecatory disorders are a common cause of chronic constipation in Parkinson disease.Neurogastroenterology and motility · 2024Article
- The rectum, anal sphincter and puborectalis muscle show different contraction wave forms during prolonged measurement with a simulated feces.Scientific reports · 2024Article
- Review
- Colorectal motility patterns and psychiatric traits in functional constipation and constipation-predominant irritable bowel syndrome: A study from China.World journal of gastroenterology · 2023Article
- Optimizing the Utility of Anorectal Manometry for Diagnosis and Therapy: A Roundtable Review and Recommendations.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2023Review
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
BACKGROUND &
aimsThe utility of high-resolution anorectal manometry (HR-ARM) for diagnosing defecatory disorders (DDs) is unclear because healthy people may have features of dyssynergia. We aimed to identify objective diagnostic criteria for DD and to ascertain the utility of HR-ARM for diagnosing DD.
methodsConstipated patients were assessed with HR-ARM and rectal balloon expulsion time (BET), and a subset underwent defecography. Normal values were established by assessing 184 sex-matched healthy individuals. Logistic regression models evaluated the association of abnormal HR-ARM findings with prolonged BET and reduced rectal evacuation (determined by defecography).
resultsA total of 474 constipated individuals (420 women) underwent HR-ARM and BET, and 158 underwent defecography. BET was prolonged, suggesting a DD, for 152 patients (32%). Rectal evacuation was lower for patients with prolonged vs normal BET. A lower rectoanal gradient during evacuation, reduced anal squeeze increment, and reduced rectal sensation were independently associated with abnormal BETs; the rectoanal gradient was 36% sensitive and 85% specific for prolonged BET. A lower rectoanal gradient and prolonged BET were independently associated with reduced evacuation. Among constipated patients, the probability of reduced rectal evacuation was 14% when the gradient and BET were both normal, 45% when either was abnormal, and 75% when both variables were abnormal.
conclusionsHR-ARM, BET, and defecography findings were concordant for constipated patients, and reduced rectoanal gradient was the best HR-ARM predictor of prolonged BET or reduced rectal evacuation. Prolonged BET, reduced gradient, and reduced evacuation each independently supported a diagnosis of DD in constipated patients. We propose the terms probable DD for patients with an isolated abnormal gradient or BET and definite DD for patients with abnormal results from both tests.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.