Evidence map›Paper›PMID 35995050›Full record

ReviewAnnual review of nutrition2022

Folic Acid and the Prevention of Birth Defects: 30 Years of Opportunity and Controversies.

Krista S Crider, Yan Ping Qi, Lorraine F Yeung, Cara T Mai, Lauren Head Zauche, Arick Wang, Kelicia Daniels, Jennifer L Williams

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Annual review of nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed, 4 pooled it
18.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

80 citing papers in PubMed, 4 syntheses or guidelines pooled it, 115 citations in OpenAlex.

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20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Krista S CriderNeural Tube Defects Surveillance and Prevention Team, Infant Outcomes Monitoring, Research, and Prevention Branch, Division of Birth Defects and Infant Disorders, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia, USA; email: kcrider@cdc.gov.
Yan Ping QiNeural Tube Defects Surveillance and Prevention Team, Infant Outcomes Monitoring, Research, and Prevention Branch, Division of Birth Defects and Infant Disorders, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia, USA; email: kcrider@cdc.gov.
Lorraine F YeungNeural Tube Defects Surveillance and Prevention Team, Infant Outcomes Monitoring, Research, and Prevention Branch, Division of Birth Defects and Infant Disorders, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia, USA; email: kcrider@cdc.gov.
Cara T MaiNeural Tube Defects Surveillance and Prevention Team, Infant Outcomes Monitoring, Research, and Prevention Branch, Division of Birth Defects and Infant Disorders, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia, USA; email: kcrider@cdc.gov.
Lauren Head ZaucheOak Ridge Institute for Science and Education, Oak Ridge, Tennessee, USA.
Arick WangNeural Tube Defects Surveillance and Prevention Team, Infant Outcomes Monitoring, Research, and Prevention Branch, Division of Birth Defects and Infant Disorders, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia, USA; email: kcrider@cdc.gov.
Kelicia DanielsEagle Global Scientific, LLC, San Antonio, Texas, USA.
Jennifer L WilliamsNeural Tube Defects Surveillance and Prevention Team, Infant Outcomes Monitoring, Research, and Prevention Branch, Division of Birth Defects and Infant Disorders, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia, USA; email: kcrider@cdc.gov.
Centers for Disease Control and Prevention · USNational Center on Birth Defects and Developmental Disabilities · USOak Ridge Associated Universities · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

For three decades, the US Public Health Service has recommended that all persons capable of becoming pregnant consume 400 μg/day of folic acid (FA) to prevent neural tube defects (NTDs). The neural tube forms by 28 days after conception. Fortification can be an effective NTD prevention strategy in populations with limited access to folic acid foods and/or supplements. This review describes the status of mandatory FA fortification among countries that fortify (

Indexed as

Folic AcidNeural Tube DefectsDietary SupplementsFemaleFood, FortifiedHumansPregnancyVitamin B 12Folic AcidVitamin B 12folic acidfortificationmeta-analysisneural tube defectsvB12

Identifiers

PMID35995050
PMCPMC9875360
OpenAlexW4293276836

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.