Evidence map›Paper›PMID 35994699›Full record

ArticleJCO oncology practice2022

Psychological Evaluation of Patients With Cancer Presenting to the Emergency Department With Pain: Independent Predictors of Worse Pain Severity, Interference, and Higher Hourly Opioid Administration.

Desiree R Azizoddin, Meghan Beck, K Mikayla Flowers, Jenna M Wilson, Peter Chai, Lily Johnsky, Gabrielle Cremone, Robert Edwards, Adriana Hasdianda, Edward Boyer and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in JCO oncology practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Symptom Networks in Postsurgical Cancer Pain Across Recovery Stages.Pain management nursing : official journal of the American Society of Pain Management Nurses · 2026
    Observational
  2. Review
  3. Article
  4. A secondary analysis: the impact of pre-existing chronic pain among patients with cancer presenting to the emergency department with acute pain.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Desiree R AzizoddinDepartment of Emergency Medicine, Brigham and Women's Hospital, Boston, MA.ORCID 0000-0001-6993-1776
Meghan BeckDepartment of Emergency Medicine, Brigham and Women's Hospital, Boston, MA.
K Mikayla FlowersDepartment of Anesthesiology Perioperative and Pain Medicine, Brigham and Women's Hospital, Boston, MA.ORCID 0000-0002-6566-046X
Jenna M WilsonDepartment of Anesthesiology Perioperative and Pain Medicine, Brigham and Women's Hospital, Boston, MA.ORCID 0000-0003-3154-0467
Peter ChaiDepartment of Emergency Medicine, Brigham and Women's Hospital, Boston, MA.
Lily JohnskyDepartment of Emergency Medicine, Brigham and Women's Hospital, Boston, MA.
Gabrielle CremoneTufts University School of Medicine, Boston, MA.
Robert EdwardsDepartment of Anesthesiology Perioperative and Pain Medicine, Brigham and Women's Hospital, Boston, MA.
Adriana HasdiandaDepartment of Emergency Medicine, Brigham and Women's Hospital, Boston, MA.ORCID 0000-0002-3100-9660
Edward BoyerDepartment of Emergency Medicine, Brigham and Women's Hospital, Boston, MA.ORCID 0000-0002-3454-1310
Kristin L SchreiberDepartment of Anesthesiology Perioperative and Pain Medicine, Brigham and Women's Hospital, Boston, MA.
Brigham and Women's Hospital · USTufts University · US

Funding

Personalizing Perioperative Preventive Analgesia: Translational Studies Investigating the Biopsychosocial Underpinnings of Enhanced Pain PropensityR35GM128691 · NIGMS · STANFORD UNIVERSITY · PI KRISTIN SCHREIBER · 2018 to 2026
$4.3M
Smart Steps: A context-aware adherence intervention to improve PrEP adherence among men who have sex with men (MSM) with substance use disorderDP2DA056107 · NIDA · BRIGHAM AND WOMEN'S HOSPITAL · PI CHAI, PETER R · 2022 to 2022
$2.7M
A novel robotic wastewater analysis system to quantify opioid exposure and treatment in residential communitiesR44DA051106 · NIDA · BIOBOT ANALYTICS, INC. · PI CHAI, PETER R, MATUS GARCIA, MARIANA G · 2020 to 2022
$1.5M
Development of Ingestible Biosensors to Enhance PrEP Adherence in Substance UsersK23DA044874 · NIDA · BRIGHAM AND WOMEN'S HOSPITAL · PI CHAI, PETER R · 2018 to 2022
$1.0M
NIDA National Early Warning System Network (iN3): An Innovative ApproachR56DA038366 · NIDA · WRIGHT STATE UNIVERSITY · PI BOYER, EDWARD W, CARLSON, ROBERT GEOFFREY · 2014 to 2014
$300k
NIDA NIH HHS DP2 DA056107NIDA NIH HHS K23 DA044874NIDA NIH HHS R44 DA051106NIDA NIH HHS R56 DA038366NIGMS NIH HHS R35 GM128691
6 · The paper itself

Abstract

purposePain is a common complaint in patients with cancer presenting to the emergency department (ED). This prospective study evaluated whether biopsychosocial factors could help predict cancer patients with risk of higher pain severity, pain interference, and opioid consumption.

methodsPatients with cancer presenting to the ED with a complaint of moderate-severe pain (≥ 4/10-numeric rating scale) completed validated self-report measures assessing sociodemographics, cancer-related treatments, pain severity and interference, medication use, and psychological symptoms (depression, anxiety, pain catastrophizing, and sleep disturbance). Opioids administered and subsequent hospitalization were abstracted. Univariable and multivariable regression analyses assessed factors associated with pain-related outcomes.

resultsParticipants (n = 175) presented with a variety of cancer types, with 76% having metastatic disease and 42% reporting current outpatient opioid use. Higher pain catastrophizing, lower depressive symptoms, lower income, outpatient opioid use, and historical chronic pain were independently associated with worse pain (

conclusionBiopsychosocial factors, particularly pain catastrophizing, remained significantly associated with worse pain outcomes for patients with cancer in the ED even after controlling for demographic and clinical variables. Patient outpatient opioid use was independently associated with worse pain, interference, and greater opioid administration, identifying this as a marker for who may benefit most from adjuvant pharmacologic and behavioral interventions.

Indexed as

Chronic PainNeoplasmsAnalgesics, OpioidEmergency Service, HospitalHumansPain MeasurementProspective StudiesAnalgesics, Opioid

Identifiers

PMID35994699
PMCPMC9810145
OpenAlexW4292980475

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.