Evidence map›Paper›PMID 35994656›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Wildlife susceptibility to infectious diseases at global scales.

Ángel L Robles-Fernández, Diego Santiago-Alarcon, Andrés Lira-Noriega

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Wildlife susceptibility to infectious diseases at global scales.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ángel L Robles-FernándezFacultad de Física, Universidad Veracruzana, 91000 Xalapa, México.ORCID 0000-0002-4674-4270
Diego Santiago-AlarconDepartment of Integrative Biology, University of South Florida, Tampa, FL 33620.ORCID 0000-0002-4914-5580
Andrés Lira-NoriegaRed de Estudios Moleculares Avanzados, Instituto de Ecología, A.C., 91073 Xalapa, México.ORCID 0000-0002-3219-0019

Funding

Tolerance and resistance responses of African bats to viral antigens: Immunological tradeoffs in zoonotic reservoir hosts.R01AI151144 · NIAID · BUCKNELL UNIVERSITY · PI FIELD, KENNETH A, REEDER, DEEANN · 2021 to 2025
$3.0M
Intelligently predicting viral spillover risks from bats and other wild mammalsR21AI164268 · NIAID · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI REEDER, DEEANN, UPHAM, NATHAN STEADMAN · 2021 to 2022
$433k
NIAID NIH HHS R01 AI151144NIAID NIH HHS R21 AI164268
6 · The paper itself

Abstract

Disease transmission prediction across wildlife is crucial for risk assessment of emerging infectious diseases. Susceptibility of host species to pathogens is influenced by the geographic, environmental, and phylogenetic context of the specific system under study. We used machine learning to analyze how such variables influence pathogen incidence for multihost pathogen assemblages, including one of direct transmission (coronaviruses and bats) and two vector-borne systems (West Nile Virus [WNV] and birds, and malaria and birds). Here we show that this methodology is able to provide reliable global spatial susceptibility predictions for the studied host-pathogen systems, even when using a small amount of incidence information (i.e., [Formula: see text] of information in a database). We found that avian malaria was mostly affected by environmental factors and by an interaction between phylogeny and geography, and WNV susceptibility was mostly influenced by phylogeny and by the interaction between geographic and environmental distances, whereas coronavirus susceptibility was mostly affected by geography. This approach will help to direct surveillance and field efforts providing cost-effective decisions on where to invest limited resources.

Indexed as

Animals, WildCommunicable Diseases, EmergingDisease SusceptibilityAnimalsBird DiseasesChiropteraCoronavirusCoronavirus InfectionsDatabases, FactualEnvironmentEpidemiological MonitoringGeographyHost-Pathogen InteractionsIncidenceMachine LearningMalariadisease riskemerging infectious diseasesglobal epidemiologymachine learningOne Health

Identifiers

PMID35994656
PMCPMC9436312

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.