Trial reportClinical oral investigations2022
Treatment of multiple adjacent RT 1 gingival recessions with the modified coronally advanced tunnel (MCAT) technique and a collagen matrix or palatal connective tissue graft: 9-year results of a split-mouth randomized clinical trial.
Trial report in Clinical oral investigations, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- De-epithelialized free gingival graft versus subepithelial connective tissue graft in the treatment of gingival recession: a systematic review and meta-analysis.Medicina oral, patologia oral y cirugia bucal · 2025Pooled it
- Collagen Matrix Versus Subepithelial Connective Tissue for Recession Coverage: A Systematic Review.Oral diseases · 2025Pooled it
- Effect of a phthalocyanine mouthrinse after connective tissue graft surgery for root coverage: a randomized split-mouth clinical trial.Oral and maxillofacial surgery · 2026Trial
- Trial
- Stability of Root Coverage Outcomes After Soft-Tissue Augmentation With a Collagen Matrix With or Without rhPDGF-BB: A 3-Year Triple-Blinded, Randomised, Placebo-Controlled Trial.Journal of clinical periodontology · 2025Trial
- Comparing Connective Tissue Grafts and Collagen Matrix in Modified Coronally Advanced Tunnel Technique for RT1 Gingival Recession: A Randomized Controlled Clinical Trial.BMC oral health · 2025Trial
- Treatment of gingival recession with vestibular incision subperiosteal tunnel access and advanced platelet-rich fibrin.BMC oral health · 2025Trial
- Emerging, personalized, and minimally invasive technologies for periodontal and peri-implant soft and hard tissue regenerative therapy.Journal of periodontology · 2026Review
- Mucogingival surgery techniques: Coronally advanced flap versus tunnel approach.Journal of periodontology · 2026Review
- Soft Tissue Substitutes in Periodontal and Peri-Implant Soft Tissue Augmentation: A Systematic Review.Materials (Basel, Switzerland) · 2024Review
- Comparative analysis of clinical, patient-centered, and COL1A1 gene expression outcomes following coronally advanced flap with xenogeneic collagen matrix versus connective tissue graft in maxillary gingival recession: A parallel-arm, single-blinded randomized controlled clinical trial.Journal of oral biology and craniofacial researchArticle
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo evaluate t he long-term outcomes following treatment of RT 1 multiple adjacent gingival recessions (MAGR) using the modified coronally advanced tunnel (MCAT) with either a collagen matrix CM or a connective tissue graft (CTG). MATERIAL AND
methodsSixteen of the original 22 subjects included in a randomized, controlled split-mouth clinical trial were available for the 9-year follow-up (114 sites). Recessions were randomly treated by means of MCAT + CM (test) or MCAT + CTG (control). Complete root coverage (CRC), mean root coverage (MRC), gingival recession depth (GRD), probing pocket depth (PD), keratinized tissue width (KTW), and thickness (KGT) were compared with baseline values and with the 12-month results.
resultsAfter 9 years, CRC was observed in 2 patients, one in each group. At 9 years, MRC was 23.0 ± 44.5% in the test and 39.7 ± 35.1% in the control group (p = 0.179). The MRC reduction compared to 12 months was - 50.1 ± 47.0% and - 48.3 ± 37.7%, respectively. The upper jaw obtained 31.92 ± 43.0% of MRC for the test and 51.1 ± 27.8% for the control group (p = 0.111) compared to the lower jaw with 8.3 ± 46.9% and 20.7 ± 40.3%. KTW and KGT increased for both CM and CTG together from 2.0 ± 0.7 to 3.1 ± 1.0 mm (< 0.0001). There were no statistically significant changes in PD.
conclusionThe present results indicate that (a) treatment of MAGR using MCAT in conjunction with either CM or CTG is likely to show a relapse over a period of 9 years, and (b) the outcomes obtained in maxillary areas seem to be more stable compared to the mandibular ones. CLINICAL RELEVANCE: The mean root coverage at 12 months could not be fully maintained over 9 years. On a long-term basis, the results seem to be less stable in the mandible as compared to maxillary areas.
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