Evidence map›Paper›PMID 35994100›Full record

ArticleCurrent genetics2022

Wide mutational analysis to ascertain the functional roles of eL33 in ribosome biogenesis and translation initiation.

Pilar Martín-Marcos, Álvaro Gil-Hernández, Mercedes Tamame

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Pilar Martín-MarcosInstituto de Biología Funcional y Genómica (IBFG), CSIC-Universidad de Salamanca, Zacarías González 2, 37007, Salamanca, Spain. a21141@usal.es.
Álvaro Gil-HernándezInstituto de Biología Funcional y Genómica (IBFG), CSIC-Universidad de Salamanca, Zacarías González 2, 37007, Salamanca, Spain.
Mercedes TamameInstituto de Biología Funcional y Genómica (IBFG), CSIC-Universidad de Salamanca, Zacarías González 2, 37007, Salamanca, Spain. tamame@usal.es.
Universidad de Salamanca · ESInstituto de Biología Funcional y Genómica · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An extensive mutational analysis of RPL33A, encoding the yeast ribosomal protein L33A (eL33) allowed us to identify several novel rpl33a mutants with different translational phenotypes. Most of the rpl33a mutants are defective in the processing of 35S and 27S pre-rRNA precursors and the production of mature rRNAs, exhibiting reductions in the amounts of ribosomal subunits and altered polysome profiles. Some of the rpl33a mutants exhibit a Gcd

Indexed as

Ribosomal ProteinsSaccharomyces cerevisiae ProteinsBasic-Leucine Zipper Transcription FactorsRibosomesRNA PrecursorsRNA, RibosomalSaccharomyces cerevisiaeBasic-Leucine Zipper Transcription FactorsGCN4 protein, S cerevisiaeMRPL33 protein, S cerevisiaeRibosomal ProteinsRNA PrecursorsRNA, RibosomalSaccharomyces cerevisiae ProteinseL33GCN4RibosomerRNA processingTranslationYeast

Identifiers

PMID35994100
PMCPMC9700599
OpenAlexW4292589873

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.