Evidence map›Paper›PMID 35993799›Full record

ArticleThe journal of spinal cord medicine2024

Treatments perceived to be helpful for neuropathic pain after traumatic spinal cord injury: A multicenter cross-sectional survey study.

Thomas N Bryce, Chung-Ying Tsai, Andrew D Delgado, Sara J Mulroy, Abigail Welch, Diana D Cardenas, Heather B Taylor, Elizabeth R Felix

Abstract readMulticenter Study
In one paragraph

Article in The journal of spinal cord medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Thomas N BryceDepartment of Rehabilitation and Human Performance, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Chung-Ying TsaiDepartment of Rehabilitation and Human Performance, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Andrew D DelgadoDepartment of Rehabilitation and Human Performance, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Sara J MulroyPathokinesiology Laboratory, Rancho Los Amigo National Rehabilitation Center, Downey, California, USA.
Abigail WelchCraig Hospital, Englewood, Colorado, USA.
Diana D CardenasDepartment of Physical Medicine and Rehabilitation, University of Miami, Miami, Florida, USA.
Heather B TaylorDepartment of Physical Medicine & Rehabilitation, The University of Texas Health Science Center at Houston, Houston, Texas, USA.
Elizabeth R FelixDepartment of Physical Medicine and Rehabilitation, University of Miami, Miami, Florida, USA.

Funding

ACL HHS 90SI5015ACL HHS 90SI5017ACL HHS 90SI5018ACL HHS 90SI5019ACL HHS 90SI5023ACL HHS 90SI5027
6 · The paper itself

Abstract

designCross-sectional survey.

objectiveTo evaluate the perceived helpfulness of pharmacological and non-pharmacological interventions and their combinations for neuropathic pain (NeuP) and subcategories of NeuP after spinal cord injury (SCI).

settingSix Spinal Cord Injury Model System Centers.

methodsThree hundred ninety one individuals at least one year post traumatic SCI were enrolled. A telephone survey was conducted to determine the pharmacologic and non-pharmacologic treatments used in the last 12 months for each participant's three worst pains, whether these treatments were "helpful", and if currently used, each treatments' effectiveness.

resultsTwo hundred twenty participants (56%) reported 354 distinct NeuPs. Pharmacological treatments rated helpful for NeuP were non-tramadol opioids (opioids were helpful for 86% of opioid treated NeuPs), cannabinoids (83%), and anti-epileptics (79%). Non-pharmacological treatments rated helpful for NeuP were massage (76%), body position adjustment (74%), and relaxation therapy (70%). Those who used both opioids and exercise reported greater NeuP treatment helpfulness compared to participants using opioids without exercise (P = 0.03).

conclusionsOpioids, cannabinoids, and massage were reported more commonly as helpful than treatments recommended as first-line therapies by current clinical practice guidelines (CPGs) for NeuP after SCI (antiepileptics and antidepressants). Individuals with SCI likely value the modulating effects of pharmacological and non-pharmacological treatments on the affective components of pain in addition to the sensory components of pain when appraising treatment helpfulness.

Indexed as

NeuralgiaSpinal Cord InjuriesAdultAgedAnalgesics, OpioidCross-Sectional StudiesFemaleHumansMaleMiddle AgedAnalgesics, OpioidNeuropathic painNon-pharmacological treatmentOpioidsPharmacological treatmentSpinal cord injury

Identifiers

PMID35993799
PMCPMC11044759

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.