Evidence map›Paper›PMID 35993728›Full record

ArticlemBio2022

Microbial Analysis of Umbilical Cord Blood Reveals Novel Pathogens Associated with Stillbirth and Early Preterm Birth.

Emilie L Vander Haar, Guojun Wu, Cynthia Gyamfi-Bannerman, Charlene Thomas, Ronald J Wapner, Uma M Reddy, Liping Zhao, Robert M Silver, Robert L Goldenberg, Yiping W Han

Open access · goldAbstract read
In one paragraph

Article in mBio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

  1. Characterizing the supragingival microbiome of healthy pregnant women.Frontiers in cellular and infection microbiology · 2022
    Trial
  2. Review
  3. Review
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  5. Review
  6. Review
  7. Article
  8. Diagnostic evaluation to identify infection-attributable stillbirth.Journal of perinatology : official journal of the California Perinatal Association · 2025
    Article
  9. Article
  10. Article
  11. Cells · 2024
    Review
  12. Article
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Emilie L Vander Haar *Department of Obstetrics and Gynecology, Vagelos College of Physicians and Surgeons, Columbia Universitygrid.239585.0grid.21729.3fgrid.239585.0 Irving Medical Center, New York, New York, USA.
Guojun Wu *Department of Biochemistry and Microbiology, School of Environmental and Biological Sciences and Center for Microbiome, Nutrition, and Health, New Jersey Institute for Food, Nutrition, and Health, Rutgers, The State University of New Jerseygrid.430387.b, New Brunswick, New Jersey, USA.
Cynthia Gyamfi-BannermanDepartment of Obstetrics and Gynecology, Vagelos College of Physicians and Surgeons, Columbia Universitygrid.239585.0grid.21729.3fgrid.239585.0 Irving Medical Center, New York, New York, USA.
Charlene ThomasDivision of Biostatistics, Department of Population Health Sciences, Weill Cornell Medicine, New York, New York, USA.
Ronald J WapnerDepartment of Obstetrics and Gynecology, Vagelos College of Physicians and Surgeons, Columbia Universitygrid.239585.0grid.21729.3fgrid.239585.0 Irving Medical Center, New York, New York, USA.
Uma M ReddyDepartment of Obstetrics and Gynecology, Vagelos College of Physicians and Surgeons, Columbia Universitygrid.239585.0grid.21729.3fgrid.239585.0 Irving Medical Center, New York, New York, USA.
Liping ZhaoDepartment of Biochemistry and Microbiology, School of Environmental and Biological Sciences and Center for Microbiome, Nutrition, and Health, New Jersey Institute for Food, Nutrition, and Health, Rutgers, The State University of New Jerseygrid.430387.b, New Brunswick, New Jersey, USA.
Robert M SilverDepartment of Obstetrics and Gynecology, University of Utah, Salt Lake City, Utah, USA.
Robert L GoldenbergDepartment of Obstetrics and Gynecology, Vagelos College of Physicians and Surgeons, Columbia Universitygrid.239585.0grid.21729.3fgrid.239585.0 Irving Medical Center, New York, New York, USA.
Yiping W HanDepartment of Obstetrics and Gynecology, Vagelos College of Physicians and Surgeons, Columbia Universitygrid.239585.0grid.21729.3fgrid.239585.0 Irving Medical Center, New York, New York, USA.
Columbia University · USRutgers, The State University of New Jersey · USWeill Cornell Medicine · USColumbia University Irving Medical Center · USUniversity of California, San Diego · USUniversity of Utah · US

Funding

Translational Research Support CoreP30ES005022 · NIEHS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI ROBERT John LAUMBACH · 1988 to 2026
$47.4M
Investigation of FadA adhesin from Fusobacterium nucleatumR01DE029532 · NIDCR · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HAN, YIPING · 2020 to 2024
$3.1M
Fusobacterium nucleatum-mediated stimulation of colorectal cancer: mechanistic studiesR01CA192111 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HAN, YIPING · 2015 to 2019
$2.1M
Mechanism of F. Nucleatum in Intrauterine InfectionR01DE023332 · NIDCR · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HAN, YIPING · 2013 to 2016
$1.6M
NCI NIH HHS R01 CA192111NIDCR NIH HHS R01 DE023332NIDCR NIH HHS R01 DE029532NIEHS NIH HHS P30 ES005022
6 · The paper itself

Abstract

Stillbirths account for half of all perinatal mortality, but the underlying cause of a significant portion of the cases remains unknown. We set out to test the potential role and extent of microbial infection in stillbirth through a case-control analysis of fetal cord blood collected from the multisite Stillbirth Collaborative Research Network. Cases (

Indexed as

Premature BirthStillbirthFemaleFetal BloodGestational AgeHumansInfant, NewbornPregnancyRNA, Ribosomal, 16SRNA, Ribosomal, 16S16S rRNAamplicon sequence variantscord bloodFusobacteriumgroup B streptococcushuman microbiomemicrobiomeoral bacteriaPCRpreterm birthstillbirthStreptococcus agalacticae

Identifiers

PMID35993728
PMCPMC9600380
OpenAlexW4292608050

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.