Evidence map›Paper›PMID 35993723›Full record

ArticleAntimicrobial agents and chemotherapy2022

Persistence of Residual Submicroscopic P. falciparum Parasitemia following Treatment of Artemether-Lumefantrine in Ethio-Sudan Border, Western Ethiopia.

Geletta Tadele, Fatou K Jaiteh, Mary Oboh, Eniyou Oriero, Sisay Dugassa, Alfred Amambua-Ngwa, Lemu Golassa

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Observational
  2. Article
  3. Molecular investigation ofBMJ global health · 2025
    Article
  4. Article
  5. Article
  6. Observational
  7. Day 3 parasitemia andmedRxiv : the preprint server for health sciences · 2024
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Geletta TadeleAklilu Lemma Institute of Pathobiology, Addis Ababa Universitygrid.7123.7, Addis Ababa, Ethiopia.ORCID 0000-0001-7754-2375
Fatou K JaitehMedical Research Council Unit the Gambia, London School of Hygiene and Tropical Medicine, Banjul, Gambia.
Mary ObohMedical Research Council Unit the Gambia, London School of Hygiene and Tropical Medicine, Banjul, Gambia.
Eniyou OrieroMedical Research Council Unit the Gambia, London School of Hygiene and Tropical Medicine, Banjul, Gambia.ORCID 0000-0002-7911-6457
Sisay DugassaAklilu Lemma Institute of Pathobiology, Addis Ababa Universitygrid.7123.7, Addis Ababa, Ethiopia.
Alfred Amambua-NgwaMedical Research Council Unit the Gambia, London School of Hygiene and Tropical Medicine, Banjul, Gambia.
Lemu GolassaAklilu Lemma Institute of Pathobiology, Addis Ababa Universitygrid.7123.7, Addis Ababa, Ethiopia.
MRC Unit the Gambia · GMAddis Ababa University · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The emergence of artemisinin-resistant parasites in Africa has had a devastating impact, causing most malaria cases and related deaths reported on the continent. In Ethiopia, artemether-lumefantrine (AL) is the first-line drug for the treatment of uncomplicated falciparum malaria. This study is one of the earliest evaluations of artemether-lumefantrine (AL) efficacy in western Ethiopia, 17 years after the introduction of this drug in the study area. This study aimed at assessing PCR- corrected clinical and parasitological responses at 28 days following AL treatment. Sixty uncomplicated falciparum malaria patients were enrolled, treated with standard doses of AL, and monitored for 28 days with clinical and parasitological assessments from September 15 to December 15, 2020. Microscopy was used for patient recruitment and molecular diagnosis of P. falciparum was performed by Var gene acidic terminal sequence (

Indexed as

AntimalarialsArtemisininsMalariaMalaria, FalciparumAdolescentArtemetherArtemether, Lumefantrine Drug CombinationDisease ProgressionEthanolaminesEthiopiaFluorenesHumansParasitemiaPlasmodium falciparumSudanTreatment OutcomeAntimalarialsArtemetherArtemether, Lumefantrine Drug CombinationArtemisininsEthanolaminesFluorenestherapeutic efficacy studyuncomplicated falciparum malariawestern Ethiopia

Identifiers

PMID35993723
PMCPMC9487599
OpenAlexW4292608350

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.