Evidence map›Paper›PMID 35993615›Full record

ReviewThe British journal of radiology2022

Total-body PET: a new paradigm for molecular imaging.

Margaret E Daube-Witherspoon, Austin R Pantel, Daniel A Pryma, Joel S Karp

Abstract readReview
In one paragraph

Review in The British journal of radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Cardiovascular imaging with total-body PET.The British journal of radiology · 2026
    Review
  3. Large axial field of view PET/CT - Not just a longer PET gantry.Zeitschrift fur medizinische Physik · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Dual-Tracer Imaging on a Long-Axial-Field-of-View PET: A Proof-of-Principle Study with [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Will extended field-of-view PET/CT depopulate the graveyard of failed PET radiopharmaceuticals?Cancer imaging : the official publication of the International Cancer Imaging Society · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Margaret E Daube-WitherspoonDepartment of Radiology, University of Pennsylvania, Philadelphia, United States.
Austin R PantelDepartment of Radiology, University of Pennsylvania, Philadelphia, United States.
Daniel A PrymaDepartment of Radiology, University of Pennsylvania, Philadelphia, United States.
Joel S KarpDepartment of Radiology, University of Pennsylvania, Philadelphia, United States.ORCID 0000-0002-6154-8585

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Total body (TB) positron emission tomography (PET) instruments have dramatically changed the paradigm of PET clinical and research studies due to their very high sensitivity and capability to image dynamic radiopharmaceutical distributions in the major organs of the body simultaneously. In this manuscript, we review the design of these systems and discuss general challenges and trade-offs to maximize the performance gains of current TB-PET systems. We then describe new concepts and technology that may impact future TB-PET systems. The manuscript summarizes what has been learned from the initial sites with TB-PET and explores potential research and clinical applications of TB-PET. The current generation of TB-PET systems range in axial field-of-view (AFOV) from 1 to 2 m and serve to illustrate the benefits and opportunities of a longer AFOV for various applications in PET. In only a few years of use these new TB-PET systems have shown that they will play an important role in expanding the field of molecular imaging and benefiting clinical practice.

Indexed as

Positron-Emission TomographyTomography, X-Ray ComputedHumansMolecular ImagingRadiopharmaceuticalsRadiopharmaceuticals

Identifiers

PMID35993615
PMCPMC9733603

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.