ArticleClinical and experimental dental research2022
The effect of two calcium phosphate-containing agents on the enamel resistance of permanent molars to demineralization: An experimental study.
Article in Clinical and experimental dental research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 5 citations in OpenAlex.
- The effectiveness of novel remineralising agents in white spot lesion treatment after microabrasion.BMC oral health · 2026Article
- Bio-waste-derived hydroxyapatite from fish bone, bovine bone, and bovine teeth for enamel remineralization.Frontiers in oral health · 2026Article
- Emerging Paradigms in Preventive Dentistry: A Review of Nonfluoridated Remineralizing Agents.International journal of clinical pediatric dentistry · 2025Review
- Effect of the use of remineralization agents before resin infiltration on the treatment of initial enamel lesions: an in-vitro study.BMC oral health · 2024Article
- In vitro remineralization of adjacent interproximal enamel carious lesions in primary molars using a bioactive bulk-fill composite.BMC oral health · 2024Article
- The effect of two calcium phosphate-containing agents on the enamel resistance of permanent molars to demineralization: An experimental study.Clinical and experimental dental research · 2022Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe main purpose of this experimental study was to determine the in vitro effects of two calcium phosphate-containing agents (Remin Pro® and GC Tooth mousse™) on the enamel resistance of permanent molars to demineralization.
methodsFifty extracted human third molars were randomly divided into four groups; that is the control group and three case groups treated with Remin Pro®, GC Tooth mousse™, and sodium fluoride gel. The three case groups were treated with 0.25 ml of the paste associated with each experimental group for 5 min, kept in fluoride-free artificial saliva, and incubated at 37°C for 28 days. After the treatment regimen, 10 samples of each case group were subjected to demineralization using an acetic acid-containing solution, and remineralization using a remineralizing solution. The morphology of enamel was observed via scanning electron microscopy and their enamel calcium/phosphorus (Ca/P) ratios were measured before/after the demineralization cycle with energy-dispersive X-ray analysis. Data were statistically analyzed using one-way analysis of variance and post hoc Tukey tests.
resultsThe enamel Ca/P ratios in the case study groups were significantly higher than that of the control group before/after the demineralization regimen (p < .0001). However, the ratios were not significantly different between the case study groups after the treatment regimen and demineralization cycle (p > .05).
conclusionThe outcomes of the current study indicated that all three agents seemed to increase the enamel resistance of permanent molar teeth to demineralization.
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