Evidence map›Paper›PMID 35993371›Full record

ArticleCartilage

The Predictive Value of Early Postoperative MRI-Based Bone Marrow Parameters for Mid-Term Outcome after MACI with Autologous Bone Grafting at the Knee.

Matthias Jung, Stefan Ruschke, Dimitrios C Karampinos, Christian Holwein, Thomas Baum, Alexandra S Gersing, Fabian Bamberg, Pia M Jungmann

Open access · hybridAbstract read
In one paragraph

Article in Cartilage. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Matthias JungDepartment of Diagnostic and Interventional Radiology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.ORCID 0000-0002-1124-4284
Stefan RuschkeDepartment of Diagnostic and Interventional Radiology, School of Medicine, Technical University of Munich, Munich, Germany.
Dimitrios C KarampinosDepartment of Diagnostic and Interventional Radiology, School of Medicine, Technical University of Munich, Munich, Germany.
Christian HolweinDepartment of Orthopaedic Sports Medicine, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany.ORCID 0000-0002-1655-1435
Thomas BaumDepartment of Neuroradiology, Klinikum Rechts der Isar, School of Medicine, Technical University of Munich, Munich, Germany.
Alexandra S GersingDepartment of Diagnostic and Interventional Radiology, School of Medicine, Technical University of Munich, Munich, Germany.
Fabian BambergDepartment of Diagnostic and Interventional Radiology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Pia M JungmannDepartment of Diagnostic and Interventional Radiology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.ORCID 0000-0003-2198-3678
University of Freiburg · DETechnical University of Munich · DETUM Klinikum · DELMU Klinikum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this study was to longitudinally determine the prognostic value of early postoperative quantitative 3T-MRI (magnetic resonance imaging) parameters of subchondral bone marrow for 2-year clinical and MRI outcome after matrix-associated autologous chondrocyte implantation (MACI) with autologous bone grafting (ABG) at the knee.

designConsecutive subjects who received MACI with ABG for treatment of focal osteochondral defects received MRI follow-up 3, 6, 12, and 24 months postoperatively. Quantitative MRI included bone marrow edema-like lesion (BMEL) volume measurements and single-voxel magnetic resonance spectroscopy (MRS;

resultsAmong a total of 18 subjects (mean age: 28.7 ± 8.4 years,

conclusionLow subchondral BMEL volume and optimal restoration of the subchondral bone at early postoperative time points predict better 2-year clinical and MRI outcomes after MACI with ABG.

Indexed as

Bone Marrow DiseasesCartilage, ArticularAdultBone MarrowBone TransplantationChondrocytesEdemaHumansMagnetic Resonance ImagingMaleYoung Adultarthroscopic surgeryathletic injuriesbone marrowcartilagemagnetic resonance imagingMR spectroscopy

Identifiers

PMID35993371
PMCPMC9393675
OpenAlexW4292485136

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.