Evidence map›Paper›PMID 35993025›Full record

ArticleOxidative medicine and cellular longevity2022

Current Status and Trends of Research on Anthracycline-Induced Cardiotoxicity from 2002 to 2021: A Twenty-Year Bibliometric and Visualization Analysis.

Yu Wang, Yifei Rao, Zhijian Lin, Rina Sa, Yuling Yin, Xiaomeng Zhang, Bing Zhang

Abstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Design of New Daunorubicin Derivatives with High Cytotoxic Potential.International journal of molecular sciences · 2025
    Article
  5. Anthracycline-induced hypertension in pediatric cancer survivors: unveiling the long-term cardiovascular risks.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2024
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yu WangSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100029, China.ORCID https://orcid.org/0000-0003-2265-3742
Yifei RaoSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100029, China.ORCID https://orcid.org/0000-0002-1399-0889
Zhijian LinSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100029, China.ORCID https://orcid.org/0000-0001-5092-068X
Rina SaSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100029, China.ORCID https://orcid.org/0000-0001-8122-9277
Yuling YinSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100029, China.ORCID https://orcid.org/0000-0001-6259-4076
Xiaomeng ZhangSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100029, China.ORCID https://orcid.org/0000-0002-4190-2751
Bing ZhangSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100029, China.ORCID https://orcid.org/0000-0001-6391-5142

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anthracyclines constitute the cornerstone of numerous chemotherapy regimens for various cancers. However, the clinical application of anthracyclines is significantly limited to their dose-dependent cardiotoxicity. A comprehensive understanding of the current status of anthracycline-induced cardiotoxicity is necessary for in-depth research and optimal clinical protocols. Bibliometric analysis is widely applied in depicting development trends and tracking frontiers of a specific field. The present study is aimed at revealing the status and trends of anthracycline-induced cardiotoxicity during the past two decades by employing bibliometric software including R-bibliometric, VOSviewer, and CiteSpace. A total of 3504 publications concerning anthracycline-induced cardiotoxicity from 2002 to 2021 were collected from the Web of Science Core Collection database. Results showed significant growth in annual yields from 90 records in 2002 to 304 papers in 2021. The United States was the most productive country with the strongest collaboration worldwide in the field. Charles University in the Czech Republic was the institution that contributed the most papers, while 7 of the top 10 productive institutions were from the United States. The United States Department of Health and Human Services and the National Institutes of Health are the two agencies that provide financial support for more than 50% of sponsored publications. The research categories of included publications mainly belong to Oncology and Cardiac Cardiovascular Systems. The Journal of Clinical Oncology had a comprehensive impact on this research field with the highest IF value and many publications. Simunek Tomas from Charles University contributed the most publications, while Lipshultz Steven E. from the State University of New York possessed the highest

Indexed as

AnthracyclinesCardiotoxicityBibliometricsDatabases, FactualHumansUnited StatesAnthracyclines

Identifiers

PMID35993025
PMCPMC9388240

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.