Evidence map›Paper›PMID 35992968›Full record

ReviewMedComm2022

Sub-lineages of the SARS-CoV-2 Omicron variants: Characteristics and prevention.

Ailan Xu, Bixia Hong, Fuxing Lou, Shuqi Wang, Wenye Li, Amna Shafqat, Xiaoping An, Yunwei Zhao, Lihua Song, Yigang Tong and 1 more

Abstract readReview
In one paragraph

Review in MedComm, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ailan XuCollege of Life Science and Technology Beijing University of Chemical Technology Beijing China.
Bixia HongCollege of Life Science and Technology Beijing University of Chemical Technology Beijing China.
Fuxing LouCollege of Life Science and Technology Beijing University of Chemical Technology Beijing China.
Shuqi WangCollege of Life Science and Technology Beijing University of Chemical Technology Beijing China.
Wenye LiCollege of Life Science and Technology Beijing University of Chemical Technology Beijing China.
Amna ShafqatCollege of Life Science and Technology Beijing University of Chemical Technology Beijing China.
Xiaoping AnCollege of Life Science and Technology Beijing University of Chemical Technology Beijing China.
Yunwei ZhaoThe First Affiliated Hospital of Jiamusi University Jiamusi China.
Lihua SongCollege of Life Science and Technology Beijing University of Chemical Technology Beijing China.
Yigang TongCollege of Life Science and Technology Beijing University of Chemical Technology Beijing China.
Huahao FanCollege of Life Science and Technology Beijing University of Chemical Technology Beijing China.ORCID https://orcid.org/0000-0001-5007-2158

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the start of the coronavirus disease 2019 (COVID-19) pandemic, new variants of severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) have emerged, accelerating the spread of the virus. Omicron was defined by the World Health Organization in November 2021 as the fifth "variant of concern" after Alpha, Beta, Gamma, and Delta. In recent months, Omicron has become the main epidemic strain. Studies have shown that Omicron carries more mutations than Alpha, Beta, Gamma, Delta, and wild-type, facilitating immune escape and accelerating its transmission. This review focuses on the Omicron variant's origin, transmission, main biological features, subvariants, mutations, immune escape, vaccination, and detection methods. We also discuss the appropriate preventive and therapeutic measures that should be taken to address the new challenges posed by the Omicron variant. This review is valuable to guide the surveillance, prevention, and development of vaccines and other therapies for Omicron variants. It is desirable to develop a more efficient vaccine against the Omicron variant and take more effective measures to constrain the spread of the epidemic and promote public health.

Indexed as

immune escapeneutralizing antibodiesOmicron variantSARS‐CoV‐2vaccination

Identifiers

PMID35992968
PMCPMC9380698

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.