Is Mexico's population hesitant towards COVID-19 vaccines? A 2021 survey on different levels of hesitancy and its determinants.

Vaccine hesitancy is a well-known phenomenon whereby individuals in a population reject or delay being vaccinated despite having access to vaccine services. This phenomenon is especially problematic in the current context of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) pandemic because vaccine hesitancy can decrease vaccination rates. In Mexico, vaccine hesitancy has been less thoroughly studied than in other countries such as the United States despite its importance and the potential impact of overlooking the problem. Understanding and effectively tackling this problem requires a more in-depth analysis of the defining characteristics of vaccination hesitancy. For this purpose, the World Health Organization's (WHO) Vaccine Hesitancy Determinants Matrix (VHDM in this study) is highly useful. In the present study, a digital survey was conducted using Google Forms to assess the level of vaccine hesitancy in the Mexican population and the vaccine determinants of the VHDM model associated with the respondents' different levels of vaccine hesitancy. The sample consisted of 1,195 people divided into four levels of vaccine hesitancy based on their answers. Tests for association were performed, identifying an association between some determinants of the VHDM model and the levels of vaccine hesitancy. Based on the analysis of the survey results, areas of opportunity for addressing COVID-19 vaccine hesitancy in Mexico were found and discussed; these included the importance of studying vaccine hesitancy as a complex and changing gradient, the high connectivity of people with high level of vaccine hesitancy to networks of people with vaccine hesitancy, the relatively high trust in physicians at all levels of vaccine hesitancy, the low trust in government authorities at high and moderate levels of vaccine hesitancy, and the strong association of the fear of suffering side effects and knowing people who have suffered them with the level of vaccine hesitancy.