Evidence map›Paper›PMID 35992827›Full record

SynthesisFrontiers in oncology2022

Efficacy and safety of indocyanine green tracer-guided lymph node dissection in minimally invasive radical gastrectomy for gastric cancer: A systematic review and meta-analysis.

Jixiang Zhao, Ke Li, Zikang Wang, Qingqing Ke, Jiapu Li, Yizhen Zhang, Xiaojiang Zhou, Yunzhi Zou, Conghua Song

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jixiang ZhaoDepartment of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Ke LiDepartment of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Zikang WangDepartment of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Qingqing KeDepartment of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Jiapu LiDepartment of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Yizhen ZhangDepartment of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Xiaojiang ZhouDepartment of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Yunzhi ZouDepartment of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Conghua SongDepartment of Gastroenterology, The Affiliated Hospital (Group) of Putian University, Putian, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The implementation of indocyanine green (ICG) tracer-guided lymph node dissection is still in the preliminary stages of laparoscopic surgery, and its safety and efficacy for gastric cancer remain unclear. Methods: A systematic review was conducted in PubMed, Embase, Web of Science, the Cochrane Library, and Scopus to identify relevant subjects from inception to June 2022. The core indicators were the total number of harvested lymph nodes and the safety of the laparoscopic gastrectomy with ICG. A meta-analysis was performed to estimate the pooled weighted mean difference (WMD) and 95% confidence interval (CI). Results: Thirteen studies and 2,027 participants were included (642 for the ICG-group and 1,385 for the non-ICG group). The mean number of lymph nodes dissected in the ICG group was significantly greater than that in the non-ICG group (WMD = 6.24, 95% CI: 4.26 to 8.22, Conclusion: ICG tracer with favorable safety increases the number of harvested lymph nodes but not the number of positive lymph nodes in laparoscopic gastrectomy. More high-quality, large-sample-size randomized controlled trials are still needed to enhance this evidence.

Indexed as

efficacygastric cancerindocyanine greenlaparoscopic gastrectomysafety

Identifiers

PMID35992827
PMCPMC9388933

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.