Evidence map›Paper›PMID 35992727›Full record

ArticleParkinson's disease2022

Short-Term Motor Outcomes in Parkinson's Disease after Subthalamic Nucleus Deep Brain Stimulation Combined with Post-Operative Rehabilitation: A Pre-Post Comparison Study.

Kazunori Sato, Yoshihide Hokari, Eriko Kitahara, Nana Izawa, Kozo Hatori, Kaoru Honaga, Genko Oyama, Taku Hatano, Hirokazu Iwamuro, Atsushi Umemura and 3 more

Open access · goldAbstract read
In one paragraph

Article in Parkinson's disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 4 pooled it
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 4 syntheses or guidelines pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  4. Pooled it
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Kazunori SatoDepartment of Rehabilitation Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.ORCID https://orcid.org/0000-0002-4292-3095
Yoshihide HokariDepartment of Rehabilitation Medicine, Juntendo University Nerima Hospital, Tokyo, Japan.
Eriko KitaharaDepartment of Rehabilitation Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Nana IzawaDepartment of Rehabilitation Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Kozo HatoriDepartment of Rehabilitation Medicine, Juntendo University Urayasu Hospital, Tokyo, Japan.
Kaoru HonagaDepartment of Rehabilitation Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Genko OyamaDepartment of Neurology, Juntendo University Hospital, Tokyo, Japan.ORCID https://orcid.org/0000-0001-7985-5367
Taku HatanoDepartment of Neurology, Juntendo University Hospital, Tokyo, Japan.
Hirokazu IwamuroDepartment of Research and Therapeutics for Movement Disorders, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Atsushi UmemuraDepartment of Research and Therapeutics for Movement Disorders, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Yasushi ShimoDepartment of Neurology, Juntendo University Nerima Hospital, Tokyo, Japan.
Nobutaka HattoriDepartment of Neurology, Juntendo University Hospital, Tokyo, Japan.
Toshiyuki FujiwaraDepartment of Rehabilitation Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Juntendo University · JPJuntendo University Hospital · JPJuntendo University Nerima Hospital · JPJuntendo University Urayasu Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The effects of subthalamic nuclear deep brain stimulation therapy (STN-DBS) and combined postoperative rehabilitation for patients with Parkinson's disease with postural instability have yet to be well reported. This study investigated the effects of short-term postoperative rehabilitation with STN-DBS on physical function in patients with Parkinson's disease. Methods: Patients diagnosed with Parkinson's disease who were admitted to our hospital for STN-DBS surgery were included in this study. Data were prospectively collected and retrospectively analyzed. Postoperative rehabilitation consisted of muscle-strengthening exercises, stretching, and balance exercises for 40-60 minutes per day for approximately 14 days. The Mini-Balance Evaluation Systems Test (Mini-BESTest), Timed Up and Go test (TUG) seconds and steps, Trunk Impairment Scale (TIS), seconds for 10 times toe-tapping, lower limb extension torque using StrengthErgo240, and center of pressure sway in the quiet standing posture were evaluated preoperatively, postoperatively, and at discharge. Mini-BESTest changes were also evaluated in the two groups classified by the presence or absence of postural instability. One-way and two-way repeated measures analyses of variance were performed for each of the three periods of change, and paired Results: A total of 60 patients with Parkinson's disease were included, and there were significant increases in Mini-BESTest, TIS, StrengthErgo240, and postural sway during closed-eye standing compared to pre- and postoperative conditions at discharge ( Conclusion: Postoperative rehabilitation combined with STN-DBS may provide short-term improvements in physical function compared with the preoperative medicated status. The improvements in gait step length and trunk function may be important factors for obtaining improvement of postoperative postural stability.

Identifiers

PMID35992727
PMCPMC9391177
OpenAlexW4290830395

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.