Evidence map›Paper›PMID 35992590›Full record

ArticleFrontiers in aging neuroscience2022

Distinct neural activation patterns of age in subcomponents of inhibitory control: A fMRI meta-analysis.

Jixin Long, Xiaoqi Song, You Wang, Chanyu Wang, Ruiwang Huang, Ruibin Zhang

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Article in Frontiers in aging neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

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8citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Jixin LongCognitive Control and Brain Healthy Laboratory, Department of Psychology, Southern Medical University, Guangzhou, China.
Xiaoqi SongCognitive Control and Brain Healthy Laboratory, Department of Psychology, Southern Medical University, Guangzhou, China.
You WangCognitive Control and Brain Healthy Laboratory, Department of Psychology, Southern Medical University, Guangzhou, China.
Chanyu WangCognitive Control and Brain Healthy Laboratory, Department of Psychology, Southern Medical University, Guangzhou, China.
Ruiwang HuangSchool of Psychology, South China Normal University, Guangzhou, China.
Ruibin ZhangCognitive Control and Brain Healthy Laboratory, Department of Psychology, Southern Medical University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inhibitory control (IC) is a fundamental cognitive function showing age-related change across the healthy lifespan. Since different cognitive resources are needed in the two subcomponents of IC (cognitive inhibition and response inhibition), regions of the brain are differentially activated. In this study, we aimed to determine whether there is a distinct age-related activation pattern in these two subcomponents. A total of 278 fMRI articles were included in the current analysis. Multilevel kernel density analysis was used to provide data on brain activation under each subcomponent of IC. Contrast analyses were conducted to capture the distinct activated brain regions for the two subcomponents, whereas meta-regression analyses were performed to identify brain regions with distinct age-related activation patterns in the two subcomponents of IC. The results showed that the right inferior frontal gyrus and the bilateral insula were activated during the two IC subcomponents. Contrast analyses revealed stronger activation in the superior parietal lobule during cognitive inhibition, whereas stronger activation during response inhibition was observed primarily in the right inferior frontal gyrus, bilateral insula, and angular gyrus. Furthermore, regression analyses showed that activation of the left anterior cingulate cortex, left inferior frontal gyrus, bilateral insula, and left superior parietal lobule increased and decreased with age during cognitive inhibition and response inhibition, respectively. The results showed distinct activation patterns of aging for the two subcomponents of IC, which may be related to the differential cognitive resources recruited. These findings may help to enhance knowledge of age-related changes in the activation patterns of IC.

Indexed as

agingcognitive inhibitionfMRIinhibitory controlresponse inhibition

Identifiers

PMID35992590
PMCPMC9389163

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