Evidence map›Paper›PMID 35992550›Full record

ArticleContrast media & molecular imaging2022

Study on the Cytotoxic Microstructure of Titanium Dioxide Nanoparticles by X-Ray Phase-Contrast CT Imaging.

Jingtong Fei, Shanshan Nie, Bo Zhang, Xinli Teng, Ying Chen, Yikun Qu, Zhuoxin Cheng, Linqi Guo

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in Contrast media & molecular imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jingtong FeiThe First Affiliated Hospital of Jiamusi University, Intensive Care Unit, Jia Mu Si 154000, China.
Shanshan NieThe First Affiliated Hospital of Jiamusi University, Intensive Care Unit, Jia Mu Si 154000, China.
Bo ZhangJiamusi University, Department of Pathophysiology, Jia Mu Si 154000, China.
Xinli TengThe Tumor Hospital of Jiamusi, Department of Tumor, Jia Mu Si 154000, China.
Ying ChenThe First Affiliated Hospital of Jiamusi University, Intensive Care Unit, Jia Mu Si 154000, China.
Yikun QuThe First Affiliated Hospital of Jiamusi University, Department of General Surgery, Jia Mu Si 154000, China.
Zhuoxin ChengThe First Affiliated Hospital of Jiamusi University, Department of General Surgery, Jia Mu Si 154000, China.
Linqi GuoThe First Affiliated Hospital of Jiamusi University, Department of General Surgery, Jia Mu Si 154000, China.ORCID 0000-0002-3381-9579
First Affiliated Hospital of Jiamusi University · CNJiamusi University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To address the problem of microstructural analysis of titania nanoparticles with high cytotoxicity, the authors propose X-ray phase-comparative CT imaging studies. In this method, the HE-stained section samples were compared with the X-ray phase-contrast CT imaging microscopic images, and 3D texture analysis was used to observe the changes in the preparation of hepatocyte microstructures in the two groups. The results show that X-ray phase-contrast CT imaging microscopic images and their larger image size are closely related to HE staining images, and X-ray phase-contrast CT microscopic images can observe important data of hepatocytes from multiple angles. The ship skeleton extraction method based on the endpoint limit also has advantages over traditional algorithms in extraction accuracy and can provide more 3D feature files, confirming the growth and transformation of normal hepatocytes into hepatocyte cytotoxic microstructures. The distribution effect of using the ensemble process is better than the simple 2D feature set and 3D feature set, and the overall accuracy is improved; the result distribution of the tree determination and random forest methods is also better than that of the support vector machine method. The experimental results show that the X-ray phase-contrast CT images can highlight the 2D and 3D imaging features of the hepatotoxic microstructure of TiO

Indexed as

NanoparticlesTomography, X-Ray ComputedAlgorithmsImaging, Three-DimensionalTitaniumX-RaysTitaniumtitanium dioxide

Identifiers

PMID35992550
PMCPMC9356853
OpenAlexW4288855673

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.