ReviewJAMIA open2022
Digital twins to enable better precision and personalized dementia care.
Review in JAMIA open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Exploring Professionals' Perceptions of the Potential of Digital Twins in Homecare-A Focus Group Study in Sweden.Healthcare (Basel, Switzerland) · 2026Article
- Digital twins for personalized treatment in uro-oncology in the era of artificial intelligence.Nature reviews. Urology · 2026Review
- Time Series Models of the Human Heart in Patients with Heart Failure: Toward a Digital Twin Approach.Sensors (Basel, Switzerland) · 2025Article
- Ethical and Quality of Care-Related Challenges of Digital Health Twins in Care Settings for Older Adults: Scoping Review.JMIR aging · 2025Article
- Digital Twin Cognition: AI-Biomarker Integration in Biomimetic Neuropsychology.Biomimetics (Basel, Switzerland) · 2025Review
- The Potential Use of Digital Twin Technology for Advancing CAR-T Cell Therapy.Current issues in molecular biology · 2025Review
- Utilization of precision medicine digital twins for drug discovery in Alzheimer's disease.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025Review
- The translational power of Alzheimer's-based organoid models in personalized medicine: an integrated biological and digital approach embodying patient clinical history.Frontiers in cellular neuroscience · 2025Review
- Digital Twins Use in Plastic Surgery: A Systematic Review.Journal of clinical medicine · 2024Review
- Opportunities for use of neuroimaging in de-risking drug development and improving clinical outcomes in psychiatry: an industry perspective.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Review
- Digital Twins in Neuroscience.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Digital twins for health: a scoping review.NPJ digital medicine · 2024Article
- Ethical and Quality of Care-Related Challenges of Digital Health Twins in Older Care Settings: Protocol for a Scoping Review.JMIR research protocols · 2024Article
- SynTwin: A graph-based approach for predicting clinical outcomes using digital twins derived from synthetic patients.Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing · 2024Article
- Review
- Toward precision medicine using a "digital twin" approach: modeling the onset of disease-specific brain atrophy in individuals with multiple sclerosis.Scientific reports · 2023Article
- Intelligent Digital Twins for Personalized Migraine Care.Journal of personalized medicine · 2023Review
- Toward Precision Medicine Using a "Digital Twin" Approach: Modeling the Onset of Disease-Specific Brain Atrophy in Individuals with Multiple Sclerosis.Research square · 2023Article
- Unveiling the potential of digital twins in homecare: A reflexive thematic analysis of older adults' views.Digital healthArticle
- Digital twins in dementia: Early evidence and future directions for precision psychiatry.Industrial psychiatry journalArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this perspective paper, we want to highlight the potential benefits of incorporating digital twins to support better dementia care. In particular, we assert that, by doing so, it is possible to ensure greater precision regarding dementia care while simultaneously enhancing personalization. Digital twins have been used successfully in manufacturing to enable better prediction and tailoring of solutions to meet required needs, and thereby have enabled more effective and efficient deployment of resources. We develop a model for digital twin in the healthcare domain as a clinical decision support tool by extrapolating its current uses from the manufacturing domain. We illustrate the power of the developed model in the context of dementia. Given the rapid rise of chronic conditions and the pressures on healthcare delivery to provide high quality, cost-effective care anywhere and anytime, we assert that such an approach is consistent with a value-based healthcare philosophy and thus important as the numbers of people with dementia continues to grow exponentially and this pressing healthcare issue is yet to be optimally addressed. Further research and development in this rapidly evolving domain is a strategic priority for ensuring the delivery of superior dementia care.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.