Evidence map›Paper›PMID 35992211›Full record

ArticleAnnals of medicine and surgery (2012)2022

Validation of R-hf risk score for risk stratification in ischemic heart failure patients: A prospective cohort study.

Rajesh Rajan, Suman Omana Soman, Mohammed Al Jarallah, Zhanna Kobalava, Raja Dashti, Ibrahim Al Zakwani, Joud Al Balool, Gary Tse, Parul Setiya, Peter A Brady and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Annals of medicine and surgery (2012), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 7 countries.

Rajesh RajanDepartment of Cardiology, Sabah Al Ahmed Cardiac Centre, Kuwait City, Kuwait.
Suman Omana SomanDepartment of Cardiology, Badr Al Samaa Hospital, Ruwi, Muscat, Oman.
Mohammed Al JarallahDepartment of Cardiology, Sabah Al Ahmed Cardiac Centre, Kuwait City, Kuwait.
Zhanna KobalavaDepartment of Internal Diseases with Courses of Cardiology and Functional Diagnostics, Peoples' Friendship University of Russia (RUDN University), Moscow, Russia.
Raja DashtiDepartment of Cardiology, Sabah Al Ahmed Cardiac Centre, Kuwait City, Kuwait.
Ibrahim Al ZakwaniDepartment of Pharmacology & Clinical Pharmacy, College of Medicine & Health Sciences, Sultan Qaboos University, Muscat, Oman.
Joud Al BaloolFaculty of Medicine, Kuwait University, Jabria, Kuwait.
Gary TseCardiovascular Analytics Group, Hong Kong, China, Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease, Department of Cardiology, Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University, Tianjin, 300211, China.
Parul SetiyaDepartment of Agrometeorology, College of Agriculture, G.B.Pant University of Agriculture & Technology, Pantnagar, Uttarakhand, India.
Peter A BradyDepartment of Cardiology, Illinois Masonic Medical Center, Chicago, IL, USA.
Ahmad Al-SaberDepartment of Mathematics and Statistics, University of Strathclyde, Glasgow, G1 1XH, UK.
Govindan VijayaraghavanDepartment of Cardiology, Kerala Institute of Medical Sciences, Kerala, India.
Al-Sabah Hospital · KWPeoples' Friendship University of Russia · RUAdvocate Illinois Masonic Medical Center · USGovind Ballabh Pant University of Agriculture and Technology · INKerala Institute of Medical Sciences · INKuwait University · KWSultan Qaboos University · OMTianjin Medical University · CNUniversity of Strathclyde · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The aim of this study was to validate R-heart failure (R-hf) risk score in ischemic heart failure patients. Methods: We prospectively recruited a cohort of 179 ischemic and 107 non-ischemic heart failure patients. This study mainly focused on ischemic heart failure patients. Non-ischemic heart failure patients were included for the purpose of validation of the risk score in various heart failure groups. Patients were stratified in high risk, moderate risk and low risk groups according to R-hf risk score. Results: A total of 179 participants with ischemic heart failure were included. Based on R-hf risk score, 82 had high risk, 50 had moderate risk and 47 had low risk heart failure scores. More than half of the patients having R-hf score of <5 had renal failure (n = 91, 50.8%) and anemia (n = 99, 55.3%). Notably, HFrEF was more prevalent in patients with high risk score (74, 90.2%). Patients with high risk score had significantly higher creatinine (2.63 ± 1.96, p < 0.001), Troponin-T HS (59.9 ± 38.0, p < 0.001) and PRO BNP (17842 ± 6684, p < 0.001) when compared to patients with low and moderate risk score. Patients with low risk score had significantly higher Hb (13.2 ± 1.85, p < 0.001), Albumin (3.69 ± 0.42, p < 0.001) and GFR (90.0 ± 8.04, p < 0.001). A R-hf score of <5 was a significant predictor of mortality in ischemic (OR = 50.34; 95% CI [16.94-194.00, p < 0.001) and non-ischemic (OR = 46.34; 95% CI [12.97-225.39], p < 0.001) heart failure patients. Conclusions: Lower R-hf risk score is a significant predictor of mortality in ischemic and non-ischemic heart failure patients. Risk score can be accessed at https://www.hfriskcalc.in.

Indexed as

Chronic kidney diseaseIschemic heart failureLeft ventricular dysfunctionMortalityR-Hf risk score

Identifiers

PMID35992211
PMCPMC9382422
OpenAlexW4289941943

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.