Evidence map›Paper›PMID 35991985›Full record

ArticleHeliyon2022

Evaluation of anthoxanthins and their actions on digestive enzyme inhibition when used independently and in combination.

Yong Qin Koh, Yu Ang Desmond Sin, Hengyang Justin Rong, Teng Hui Sean Chua, Si-Han Sherman Ho, Han Kiat Ho

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yong Qin KohDepartment of Pharmacy, Faculty of Science, National University of Singapore, Singapore.
Yu Ang Desmond SinDepartment of Pharmacy, Faculty of Science, National University of Singapore, Singapore.
Hengyang Justin RongDepartment of Pharmacy, Faculty of Science, National University of Singapore, Singapore.
Teng Hui Sean ChuaDepartment of Pharmacy, Faculty of Science, National University of Singapore, Singapore.
Si-Han Sherman HoHoow Foods Pte Ltd, 67 Ayer Rajah Crescent, Singapore.
Han Kiat HoDepartment of Pharmacy, Faculty of Science, National University of Singapore, Singapore.
National University of Singapore · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carbohydrate digestibility is a key determinant for elevated postprandial hyperglycemia (PPHG). Apart from dietary restrictions, one of the strategies to reduce PPHG is to limit the activity of carbohydrate digestive enzymes within the gastrointestinal tract in order to reduce monosaccharide absorption rates. The present work aimed to assess the inhibitory capabilities of digestive enzymes (e.g., α-glucosidase and α-amylase) by anthoxanthins when used independently, in combination with acarbose, or with a different anthoxanthin. Our results showed that quercetin, myricetin, and luteolin presented lower IC

Indexed as

AcarboseAnthoxanthinsSynergistic inhibitionα-amylaseα-glucosidase

Identifiers

PMID35991985
PMCPMC9389255
OpenAlexW4290612987

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.