Evidence map›Paper›PMID 35991551›Full record

ArticleFrontiers in genetics2022

DNA methylation patterns and gene expression from amygdala tissue of mature Brahman cows exposed to prenatal stress.

Emilie C Baker, Audrey L Earnhardt, Kubra Z Cilkiz, Haley C Collins, Brittni P Littlejohn, Rodolfo C Cardoso, Noushin Ghaffari, Charles R Long, Penny K Riggs, Ronald D Randel and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Emilie C BakerDepartment of Animal Science, Texas A&M University, College Station, TX, United States.
Audrey L EarnhardtDepartment of Animal Science, Texas A&M University, College Station, TX, United States.
Kubra Z CilkizDepartment of Animal Science, Texas A&M University, College Station, TX, United States.
Haley C CollinsDepartment of Animal Science, Texas A&M University, College Station, TX, United States.
Brittni P LittlejohnDepartment of Animal Science, Texas A&M University, College Station, TX, United States.
Rodolfo C CardosoDepartment of Animal Science, Texas A&M University, College Station, TX, United States.
Noushin GhaffariDepartment of Computer Science, Prairie View A&M University, Prairie View, TX, United States.
Charles R LongDepartment of Animal Science, Texas A&M University, College Station, TX, United States.
Penny K RiggsDepartment of Animal Science, Texas A&M University, College Station, TX, United States.
Ronald D RandelDepartment of Animal Science, Texas A&M University, College Station, TX, United States.
Thomas H WelshDepartment of Animal Science, Texas A&M University, College Station, TX, United States.
David G RileyDepartment of Animal Science, Texas A&M University, College Station, TX, United States.
Texas A&M University · USPrairie View A&M University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prenatal stress can alter postnatal performance and temperament of cattle. These phenotypic effects may result from changes in gene expression caused by stress-induced epigenetic alterations. Specifically, shifts in gene expression caused by DNA methylation within the brain's amygdala can result in altered behavior because it regulates fear, stress response and aggression in mammals Thus, the objective of this experiment was to identify DNA methylation and gene expression differences in the amygdala tissue of 5-year-old prenatally stressed (PNS) Brahman cows compared to control cows. Pregnant Brahman cows (

Indexed as

amygdalaBrahmanDNA methylationgene expressionprenatal stress

Identifiers

PMID35991551
PMCPMC9389044
OpenAlexW4289860711

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.