Evidence map›Paper›PMID 35991346›Full record

ArticleFrontiers in neural circuits2022

Future research directions to identify risks and mitigation strategies for neurostructural, ocular, and behavioral changes induced by human spaceflight: A NASA-ESA expert group consensus report.

Rachael D Seidler, Claudia Stern, Mathias Basner, Alexander C Stahn, Floris L Wuyts, Peter Zu Eulenburg

Abstract readConsensus Statement
In one paragraph

Article in Frontiers in neural circuits, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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  8. Life (Basel, Switzerland) · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rachael D SeidlerDepartment of Applied Physiology & Kinesiology, Health and Human Performance, University of Florida, Gainesville, FL, United States.
Claudia SternDepartment of Clinical Aerospace Medicine, German Aerospace Center (DLR) and ISS Operations and Astronauts Group, European Astronaut Centre, European Space Agency (ESA), Cologne, Germany.
Mathias BasnerDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Alexander C StahnDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Floris L WuytsDepartment of Physics, University of Antwerp, Antwerp, Belgium.
Peter Zu EulenburgGerman Vertigo and Balance Center, University Hospital, Ludwig-Maximilians-Universität München (LMU), Munich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A team of experts on the effects of the spaceflight environment on the brain and eye (SANS: Spaceflight-Associated Neuro-ocular Syndrome) was convened by NASA and ESA to (1) review spaceflight-associated structural and functional changes of the human brain and eye, and any interactions between the two; and (2) identify critical future research directions in this area to help characterize the risk and identify possible countermeasures and strategies to mitigate the spaceflight-induced brain and eye alterations. The experts identified 14 critical future research directions that would substantially advance our knowledge of the effects of spending prolonged periods of time in the spaceflight environment on SANS, as well as brain structure and function. They used a paired comparison approach to rank the relative importance of these 14 recommendations, which are discussed in detail in the main report and are summarized briefly below.

Indexed as

Space FlightUnited States National Aeronautics and Space AdministrationBrainHumansUnited StatesVision, Ocularastronautbrainexpert opinioneyehuman spaceflightmitigationSANSstrategies

Identifiers

PMID35991346
PMCPMC9387435

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.