Evidence map›Paper›PMID 35991187›Full record

ArticleFrontiers in physiology2022

Inferring Insulin Secretion Rate from Sparse Patient Glucose and Insulin Measures.

Rammah M Abohtyra, Christine L Chan, David J Albers, Bruce J Gluckman

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Rammah M AbohtyraCenter for Neural Engineering, The Pennsylvania State University, University Park, PA, United States.
Christine L ChanSection of Pediatric Endocrinology, University of Colorado School of Medicine, Aurora, CO, United States.
David J AlbersDepartment of Bioengineering, University of Colorado School of Medicine, Aurora, CO, United States.
Bruce J GluckmanCenter for Neural Engineering, The Pennsylvania State University, University Park, PA, United States.
Pennsylvania State University · USUniversity of Colorado Denver · US

Funding

University of Colorado Anschutz Medical Campus DRCP30DK116073 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI PETER J DEMPSEY · 2020 to 2026
$10.8M
Mechanistic Machine LearningR01LM012734 · NLM · UNIVERSITY OF COLORADO DENVER · PI ALBERS, DAVID J., GLUCKMAN, BRUCE J · 2017 to 2019
$2.0M
NIDDK NIH HHS P30 DK116073NLM NIH HHS R01 LM012734
6 · The paper itself

Abstract

The insulin secretion rate (ISR) contains information that can provide a personal, quantitative understanding of endocrine function. If the ISR can be reliably inferred from measurements, it could be used for understanding and clinically diagnosing problems with the glucose regulation system.

Indexed as

and CSR/ISR molar ratiocompartment modelsestimation algorithminsulin and C-peptideISR functionOGTT

Identifiers

PMID35991187
PMCPMC9384214
OpenAlexW4289712010

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.