Evidence map›Paper›PMID 35990718›Full record

ArticleCanadian liver journal2018

6th Canadian Symposium on Hepatitis C Virus: Delivering a cure for hepatitis C infection-What are the remaining gaps?

Sarwat Khan, Annie Bernier, Dustin Dapp, Emmanuel Fortier, Mel Krajden, Alexandra King, Jason Grebely, Selena M Sagan, Curtis L Cooper, Angela M Crawley

Open access · greenAbstract read
In one paragraph

Article in Canadian liver journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Telemedicine successfully engages marginalized rural hepatitis C patients in curative care.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2020
    Article
  4. The 8Canadian liver journal · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Sarwat KhanDepartment of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada.
Annie BernierDepartment of Microbiology and Immunology, McGill University, Montreal, Quebec, Canada.
Dustin DappFaculty of Health Sciences, Simon Fraser University, Burnaby, British Columbia, Canada.
Emmanuel FortierFaculté de Médicine, Université de Montréal, Montreal, Quebec, Canada.
Mel KrajdenBritish Columbia Center for Disease Control, Vancouver, British Columbia, Canada.
Alexandra KingDepartment of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Jason GrebelyThe Kirby Institute, University of New South Wales Sydney, Sydney, New South Wales, Australia.
Selena M SaganDepartment of Microbiology and Immunology, McGill University, Montreal, Quebec, Canada.
Curtis L CooperSchool of Epidemiology, Public Health and Preventative Medicine, University of Ottawa, Ottawa, Ontario, Canada.
Angela M CrawleyDepartment of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada.
McGill University · CAUniversité de Montréal · CAOttawa Hospital · CAOttawa Hospital Research InstituteSimon Fraser University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Estimates are that more than 250,000 people in Canada are chronically infected with hepatitis C virus (HCV), and many more are unaware of their infection status. If untreated, chronic HCV infection can lead to cirrhosis and subsequent complications such as hepatocellular carcinoma. The Canadian Network on Hepatitis C, supported by the Public Health Agency of Canada and the Canadian Institutes of Health Research, has been committed to the scientific study of chronic hepatitis C and to supporting the advocacy work to improve diagnosis and access to HCV care in Canada. Although the treatment of HCV infection has been greatly advanced with direct-acting antivirals, with cure rates as high as 95%, many challenges remain in the implementation of HCV care. These issues include the lack of an effective vaccine, infection screening, treatment failure or resistance, post-cure health issues, limitations of treatment access despite increased provincial subsidization, complex needs of at-risk populations (ie, injection drug users, societal obstacles). At the 6th Canadian Symposium on HCV in March 2017, the theme "Delivering a Cure for Hepatitis C Infection: What Are the Remaining Gaps?" provided a framework in which basic scientists, clinicians, epidemiologists, social scientists, and community members interested in HCV research in Canada could showcase how they are working to address these ongoing challenges.

Indexed as

CanHepCHCVhost–virus interactionssustained virologic response (SVR)

Identifiers

PMID35990718
PMCPMC9202794
OpenAlexW2883743870

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.