Evidence map›Paper›PMID 35990361›Full record

ArticleFrontiers in nutrition2022

Concentration and distribution of sialic acid in human milk and its correlation with dietary intake.

Qiaoling Xie, Yuhan Xu, Wei Zhang, Meizhen Zhu, Xinyue Wang, Jiale Huang, Yingying Zhuang, Hui Lan, Xiaoxuan Chen, Dongbei Guo and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 15 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Qiaoling XieSchool of Public Health, Xiamen University, Xiamen, China.
Yuhan XuSchool of Public Health, Xiamen University, Xiamen, China.
Wei ZhangSchool of Public Health, Xiamen University, Xiamen, China.
Meizhen ZhuSchool of Public Health, Xiamen University, Xiamen, China.
Xinyue WangDepartment of Clinical Nutrition, School of Medicine, Ruijin Hospital Affiliated to Shanghai Jiao Tong University, Shanghai, China.
Jiale HuangDepartment of Clinical Nutrition, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Yingying ZhuangDepartment of Clinical Nutrition, Xiamen Humanity Hospital, Xiemen, China.
Hui LanSchool of Public Health, Xiamen University, Xiamen, China.
Xiaoxuan ChenSchool of Public Health, Xiamen University, Xiamen, China.
Dongbei GuoSchool of Public Health, Xiamen University, Xiamen, China.
Hongwei LiSchool of Public Health, Xiamen University, Xiamen, China.
Xiamen University · CNNanchang University · CNRuijin Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This study evaluates the content, distribution, and changing trend of sialic acid in human milk and the correlation between dietary intake of sialic acid and that in human milk. Methods: The study included 33 mothers of full-term and exclusively breastfed infants. At least 2 ml of milk was collected on the 3rd, 8th, 30th, and 90th day after delivery, and 24-h diet recalls of the lactating mothers were obtained each time. The correlation of human milk sialic acid concentration with lactating women's dietary sialic acid intake during lactation was analyzed by statistical analysis software SPSS. Results: The average concentration of sialic acid in colostrum, transition, and 1 and 3 months were 1,670.74 ± 94.53, 1,272.19 ± 128.74, 541.64 ± 55.2, and 297.65 ± 20.78 mg/L, respectively. The total sialic acid concentration in colostrum was about 5.6 times higher than that at 3 months ( Conclusion: During the lactation period, the distribution of sialic acid in breast milk is relatively stable and its content fluctuates greatly, which may not be affected by the mother's diet, but mainly depends on the self-regulation oft physiological needs.

Indexed as

contentdietdistributionhuman milksialic acid

Identifiers

PMID35990361
PMCPMC9386340
OpenAlexW4289731165

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.