Evidence map›Paper›PMID 35990296›Full record

ArticleSisli Etfal Hastanesi tip bulteni2022

Impact of Variant Histology on Clinical and Pathological Outcomes in Patients with the Upper Urinary Tract Urothelial Carcinoma.

Meylis Artykov, Hakan Bahadır Haberal, Mesut Altan, Kemal Kosemehmetoglu, Sertac Yazici, Haluk Ozen, Bulent Akdogan

Abstract read
In one paragraph

Article in Sisli Etfal Hastanesi tip bulteni, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Meylis ArtykovDepartment of Urology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Hakan Bahadır HaberalDepartment of Urology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Mesut AltanDepartment of Urology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Kemal KosemehmetogluDepartment of Pathology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Sertac YaziciDepartment of Urology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Haluk OzenDepartment of Urology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Bulent AkdoganDepartment of Urology, Hacettepe University Faculty of Medicine, Ankara, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The objective of the study was to determine the effect of variant histology on pathological outcomes and survival in patients operated for the upper urinary tract urothelial carcinoma (UTUC). Methods: Data of 128 patients who were operated for UTUC between 2001 and 2019 were retrospectively analyzed. Patients with pure urothelial carcinoma and patients with variant histology were compared in terms of demographics, pathological outcomes, and survival. Results: The mean age of the patients was 65±11 years, female to male ratio was 30/98 and median follow-up period was 26.5 (1-176) months. Variant histology was detected in 14.8% of patients. Variant histology was found to be associated with surgical margin positivity, lymph node metastasis, presence of lymphovascular invasion, high tumor stage and grade (p=0.001, p=0.012, p=0.001, p=0.002, and p=0.009, respectively). Three-year cancer-specific and overall survival rates were 79.6% and 77.3%, respectively. There was no statistically significant relationship between variant histology with cancer-specific and overall survival (p=0.514 and p=0.515, respectively). Conclusion: Variant histology of UTUC was found to be associated with locally advanced disease, but its effect on survival could not be demonstrated.

Indexed as

Survival analysisupper system transitional epithelial cell carcinomavariant histology

Identifiers

PMID35990296
PMCPMC9350051

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.