Evidence map›Paper›PMID 35990223›Full record

ReviewCanadian liver journal2019

Cystic fibrosis liver disease: A condition in need of structured transition and continuity of care.

Julian Hercun, Fernando Alvarez, Catherine Vincent, Marc Bilodeau

Open access · greenAbstract readReview
In one paragraph

Review in Canadian liver journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Imaging of cystic fibrosis manifestations in the abdomen.Abdominal radiology (New York) · 2025
    Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Julian HercunHepatology Department, Centre Hospitalier de l'Université de Montréal, Montréal, Québec.
Fernando AlvarezGastroenterology, Hepatology and Nutrition Division, CHU Sainte-Justine, Montréal, Québec.
Catherine VincentHepatology Department, Centre Hospitalier de l'Université de Montréal, Montréal, Québec.
Marc BilodeauHepatology Department, Centre Hospitalier de l'Université de Montréal, Montréal, Québec.
Centre Hospitalier de l’Université de Montréal · CACentre Hospitalier Universitaire Sainte-Justine · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver disease affects one-third of patients with cystic fibrosis (CF) and it is one of the major causes of morbidity and mortality in these patients. Historically considered a disease of childhood, its impact is now seen more often in adulthood. The heterogeneous pattern of CF liver disease and its rapid progression to cirrhosis remain a diagnostic challenge and new questions pertaining to the nature of liver involvement have recently been raised. Non-invasive measures to stratify the severity of liver involvement are increasingly used to predict clinical outcomes. A single treatment, ursodeoxycholic acid, has been used to slow progression of liver disease while recent advances in the field of CF treatments are promising. Management of portal hypertension remains challenging but outcomes after liver transplantation are encouraging. While many questions remain unanswered, a growing number of CF patients reach adulthood and will require care for CF liver disease.

Indexed as

biliary cirrhosiscystic fibrosiscystic fibrosis liver diseasenon-invasive diagnosisportal hypertension

Identifiers

PMID35990223
PMCPMC9202747
OpenAlexW2910639362

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.