Evidence map›Paper›PMID 35990051›Full record

ArticleFrontiers in psychiatry2022

Theta oscillations: A rhythm difference comparison between major depressive disorder and anxiety disorder.

Yu Zhang, Lei Lei, Ziwei Liu, Mingxue Gao, Zhifen Liu, Ning Sun, Chunxia Yang, Aixia Zhang, Yikun Wang, Kerang Zhang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Review
  5. Article
  6. Rhythmic activity in resting-state EEG predicts trait anxiety.Imaging neuroscience (Cambridge, Mass.) · 2025
    Article
  7. Review
  8. Article
  9. Review
  10. Aperiodic neural activity is a biomarker for depression severity.medRxiv : the preprint server for health sciences · 2023
    Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Yu ZhangDepartment of Psychiatry, First Hospital of Shanxi Medical University, Taiyuan, China.
Lei LeiDepartment of Psychiatry, First Hospital of Shanxi Medical University, Taiyuan, China.
Ziwei LiuDepartment of Psychiatry, First Hospital of Shanxi Medical University, Taiyuan, China.
Mingxue GaoDepartment of Psychiatry, First Hospital of Shanxi Medical University, Taiyuan, China.
Zhifen LiuDepartment of Psychiatry, First Hospital of Shanxi Medical University, Taiyuan, China.
Ning SunDepartment of Psychiatry, First Hospital of Shanxi Medical University, Taiyuan, China.
Chunxia YangDepartment of Psychiatry, First Hospital of Shanxi Medical University, Taiyuan, China.
Aixia ZhangDepartment of Psychiatry, First Hospital of Shanxi Medical University, Taiyuan, China.
Yikun WangLaboratory of Artificial Intelligence Assisted Diagnosis and Treatment for Mental Disorder, First Hospital of Shanxi Medical University, Taiyuan, China.
Kerang ZhangDepartment of Psychiatry, First Hospital of Shanxi Medical University, Taiyuan, China.
Shanxi Medical University · CNFirst Hospital of Shanxi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Due to substantial comorbidities of major depressive disorder (MDD) and anxiety disorder (AN), these two disorders must be distinguished. Accurate identification and diagnosis facilitate effective and prompt treatment. EEG biomarkers are a potential research hotspot for neuropsychiatric diseases. The purpose of this study was to investigate the differences in EEG power spectrum at theta oscillations between patients with MDD and patients with AN. Methods: Spectral analysis was used to study 66 patients with MDD and 43 patients with AN. Participants wore 16-lead EEG caps to measure resting EEG signals. The EEG power spectrum was measured using the fast Fourier transform. Independent samples Results: EEG power spectrum of the MDD group significantly differed from the AN group in the theta oscillation on 4-7 Hz at eight electrode points at F3, O2, T3, P3, P4, FP1, FP2, and F8. Conclusion: Participants with anxiety demonstrated reduced power in the prefrontal cortex, left temporal lobe, and right occipital regions. Confirmed by further studies, theta oscillations could be another biomarker that distinguishes MDD from AN.

Indexed as

anxiety disorderbiomarkerdiagnosisEEG power spectrummajor depressive disorder

Identifiers

PMID35990051
PMCPMC9381950
OpenAlexW4289516709

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.