Evidence map›Paper›PMID 35990031›Full record

ArticleJournal of pediatric genetics2022

Molecular Study of Childhood Steroid-Resistant Nephrotic Syndrome: A Hospital-Based Study.

Akanksha Singh, Ankur Singh, Om Prakash Mishra, Rajniti Prasad, Gopeshwar Narayan, Vineeta V Batra, Mansoureh Tabatabaeifar, Franz Schaefer

Open access · greenAbstract read
In one paragraph

Article in Journal of pediatric genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Akanksha SinghDivision of Pediatric Nephrology, Department of Pediatrics, Institute of Medical Sciences, Varanasi, Uttar Pradesh, India.
Ankur SinghDivision of Pediatric Nephrology, Department of Pediatrics, Institute of Medical Sciences, Varanasi, Uttar Pradesh, India.ORCID 0000-0002-9419-8972
Om Prakash MishraDivision of Pediatric Nephrology, Department of Pediatrics, Institute of Medical Sciences, Varanasi, Uttar Pradesh, India.
Rajniti PrasadDivision of Pediatric Nephrology, Department of Pediatrics, Institute of Medical Sciences, Varanasi, Uttar Pradesh, India.
Gopeshwar NarayanDepartment of Molecular and Human Genetics, Institute of Science, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
Vineeta V BatraDepartment of Pathology, GB Pant Hospital, New Delhi, India.
Mansoureh TabatabaeifarDivision of Pediatric Nephrology, Center for Pediatrics and Adolescent Medicine, Heidelberg University Medical Center, Heidelberg, Germany.
Franz SchaeferDivision of Pediatric Nephrology, Center for Pediatrics and Adolescent Medicine, Heidelberg University Medical Center, Heidelberg, Germany.
Institute of Medical Sciences · INHeidelberg University · DEBanaras Hindu University · INGovind Ballabh Pant Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Steroid-resistant nephrotic syndrome (SRNS) patients with genetic mutations most commonly have histology of focal segmental glomerulosclerosis (FSGS) and do not respond to immunosuppressive drugs. We report the molecular screening results of 18 pediatric SRNS cases presented to our nephrology clinic. Three pathogenic variants have been detected, two previously reported and one novel variant. The reported pathogenic variants have been detected in

Indexed as

focal segmental glomerulosclerosisgeneticpediatricsteroid-resistant nephrotic syndrome

Identifiers

PMID35990031
PMCPMC9385261
OpenAlexW3126466345

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.