ArticleFrontiers in digital health2022
Effectiveness of a hybrid digital substance abuse prevention approach combining e-Learning and in-person class sessions.
Article in Frontiers in digital health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.
- Planning, implementation, evaluation, and sustainment of digital health interventions for adolescent substance use prevention: a systematic review of influencing factors based on the RE-AIM framework.Health education research · 2025Pooled it
- Understanding the mechanisms of change in social norms around tobacco use: A systematic review and meta-analysis of interventions.Addiction (Abingdon, England) · 2025Pooled it
- Efficacy of a Mobile Phone-Based Life-Skills Training Program for Addiction Prevention Optimized Among Adolescents With Low Program Engagement: Cluster-Randomized Controlled Trial.JMIR mHealth and uHealth · 2026Trial
- Fundamentals of leadership development: a randomized pilot study to evaluate implementation of a leadership curriculum for diversity, equity, and inclusion.Surgical endoscopy · 2025Trial
- Digital Interventions to Facilitate Screening, Brief Interventions, and Referral to Treatment for Substance Use Among Adolescents.Child and adolescent psychiatric clinics of North America · 2026Review
- Primary Prevention Interventions for Problematic Substance Use in Adolescents: A Scoping Review.Journal of prevention (2022) · 2026Review
- Using normalization process theory to evaluate the implementation of a hybrid psychosocial prevention intervention in mental health care - a qualitative interview study.BMC health services research · 2026Article
- School-Based Alcohol and Tobacco Prevention Strategies: A Scoping Review and the Missing Role of School Nurses.Children (Basel, Switzerland) · 2026Review
- SAFEGUARD: Transforming Military Suicide Prevention Through Predictive Analytics and Targeted Interventions.Current psychiatry reports · 2026Review
- Impact of a Hybrid Prevention Program for High School Students on Prescription Drug Misuse Outcomes.Behavioral sciences (Basel, Switzerland) · 2026Article
- Efficacy of an instant messaging-based life-skills training program to prevent behavioral risk factors among adolescents in Europe: study protocol of a cluster-randomized controlled trial.BMC psychology · 2025Article
- Digital Integrated Interventions for Comorbid Depression and Substance Use Disorder: Narrative Review and Content Analysis.JMIR mental health · 2025Review
- Neuroscience-informed psychoeducation for addiction: a conceptual and feasibility study.Frontiers in psychiatry · 2025Article
- The ABCD and HBCD Studies: Longitudinal Studies to Inform Prevention Science.Focus (American Psychiatric Publishing) · 2024Review
- Commentary: Effectiveness of a hybrid digital substance abuse prevention approach combining e-learning and in-person class sessions.Frontiers in digital health · 2023Article
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
Background: Effective school-based programs for preventing substance abuse offer considerable public health potential. Yet limited class time and uneven implementation fidelity can be barriers to widespread adoption and high-quality implementation. A hybrid digital approach may be effective and help address these barriers. Objective: To evaluate the effectiveness of a hybrid substance abuse prevention program for middle school students consisting of e-learning modules and in-person class sessions. Design: Twenty-three United States (U.S.) middle schools were randomly assigned either to an intervention condition (13 schools) or a treatment-as-usual control condition (10 schools) where standard health education material was delivered. There were 1,447 participants who completed the pre-test and post-test assessments, of which 48.3% were male and 51.7% female. Intervention: The hybrid digital intervention consisted of 14 brief e-learning modules and six classroom sessions adapted from an evidence-based program designed for classroom implementation to increase knowledge of adverse consequences of substance use and improve social skills, personal coping skills, and skills for resisting social influences to smoke, drink, or use drugs. Measures: Participating students completed online pre-test and post-test surveys to assess substance use, knowledge, and life skills. Results: There were significant reductions in substance use for the hybrid digital condition compared to the control condition as well as significant increases in health knowledge, skills knowledge, and life skills. Conclusions: A hybrid digital approach to substance abuse prevention is effective and offers potential for overcoming common barriers to widespread adoption and high-quality implementation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.