ArticleCureus2022
Eight Patients With Pilonidal Carcinoma in One Decade-Is the Incidence Rising?
Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The trial behind it
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Who cites it
4 citing papers in PubMed, 9 citations in OpenAlex.
- The value of honey dressings in pilonidal cyst healing: a prospective randomized single-center trial.Techniques in coloproctology · 2023Trial
- Pilonidal Disease: A Brazilian epidemiological study with an overview of 45,000 surgeries performed in the Unified Health System.Revista do Colegio Brasileiro de Cirurgioes · 2026Article
- Demographic overview of pilonidal sinus carcinoma: updated insights into the incidence.International journal of colorectal disease · 2023Article
- Treatment of metastatic squamous cell carcinoma arising in sacrococcygeal pilonidal sinus: a case report series.Frontiers in medicine · 2023Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionCarcinoma secondary to pilonidal disease is very rare with fewer than 130 reported cases so far. It is presumed that underreporting and underpublishing contribute to the low reported incidence.
methodsA post was published on a closed Facebook group with about 30,000 Syrian doctors asking if anyone had ever seen a patient with pilonidal carcinoma before. The patients' data were collected retrospectively from the treating physicians.
resultsBetween 2010 and 2019, we identified eight patients with pilonidal carcinoma. All patients were males with a mean age of 55.5 years. The mean interval between diagnosis of pilonidal disease and diagnosis of carcinoma was 6.9 years. A growing ulcer on the background of a pilonidal sinus disease was the presenting complaint in 50% of cases. Three patients were lost from follow-up after the diagnosis due to referral. All other five patients underwent surgical resection and three of them received postoperative chemoradiation. Four patients were followed for six months or longer: two died of metastases, one survived after recurrence and re-excision, and one survived with no recurrence.
conclusionThis paper presents the largest cohort of pilonidal carcinoma so far and the first that describes the disease in the Syrian population. Due to underreporting, the real incidence of pilonidal carcinoma exceeds what is reported so far in the literature.
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