Evidence map›Paper›PMID 35989722›Full record

ArticleAnnals of medicine and surgery (2012)2022

Intratympanic injection of dexamethasone for management of labyrinthitis associated with COVID-19 disease resistant cases.

Wael F Ismaiel, Mohamed H Abdelazim, Ashraf A Wahba, Mahmoud E Alsobky, Ahmed Abdalrhman Ibrahim, Soliman A Ghanem, Ali A Rabaan, Elshahat I Ismail

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of medicine and surgery (2012), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Wael F IsmaielOtorhinolaryngology Department, Faculty of Medicine, Al-Azhar University, Damietta, Egypt.
Mohamed H AbdelazimOtorhinolaryngology Department, Faculty of Medicine, Al-Azhar University, Damietta, Egypt.
Ashraf A WahbaOtorhinolaryngology Department, Faculty of Medicine, Al-Azhar University, Damietta, Egypt.
Mahmoud E AlsobkyOtorhinolaryngology Department, Faculty of Medicine, Al-Azhar University, Damietta, Egypt.
Ahmed Abdalrhman IbrahimOtorhinolaryngology Department, Faculty of Medicine, Al-Azhar University, Damietta, Egypt.
Soliman A GhanemAudiology Unit, Otorhinolaryngology Department, Faculty of Medicine, Al-Azhar University, Damietta, Egypt.
Ali A RabaanMolecular Diagnostic Laboratory, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia.
Elshahat I IsmailAudiology Unit, Otorhinolaryngology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Al-Azhar University · EGMansoura University · EGSaudi Aramco Medical Services Organization · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To evaluate the efficacy of mixed oral prednisolone and intratympanic dexamethasone (ITID) injection in labyrinthitis, due to COVID 19. Methods: Seventy-five post-COVID-19 labyrinthitis patients were included. Those patients were treated with systemic oral prednisolone for two weeks and ITID. Patients who refuse ITID were ordered to continue oral prednisolone treatment. Assessment of outcome and audiometry for hearing evaluation was done 1, 2 and 4 weeks as well as 3 months post-treatment. Results: Patients in oral steroid only group were 26 patients, while patients in oral steroid and ITID group were 49 patients. In oral steroid group; 11/26 patients showed complete recovery, 3/26 had partial recovery and 12/26 not recovered. In other group; 38/46 patients had complete recovery, 6 had partial recovery and 5/49 patients not recovered. Conclusion: Combined systemic corticosteroid with ITID showed a marked improvement of post-COVID vestibular disorder and hearing loss than only using oral corticosteroid therapy.

Indexed as

COVID-19DexamethasoneHearing lossLabyrinthitis

Identifiers

PMID35989722
PMCPMC9384350
OpenAlexW4292342905

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.