Evidence map›Paper›PMID 35989322›Full record

ArticleBMC gastroenterology2022

Anatomical pancreatic variants in intraductal papillary mucinous neoplasm patients: a cross-sectional study.

Katarina Johansson, Harri Mustonen, Hanna Seppänen, Tiina E Lehtimäki

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC gastroenterology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Meandering Main Pancreatic Duct Syndrome: a rare cause of recurrent acute pancreatitis.Journal of the Canadian Association of Gastroenterology · 2026
    Article
  3. Review
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Katarina JohanssonDepartment of Radiology, HUS Diagnostic Center, University of Helsinki and Helsinki University Hospital, PO Box 340, 00029 HUS, Helsinki, Finland. katarina.johansson@hus.fi.
Harri MustonenDepartment of Surgery, University of Helsinki and Helsinki University Hospital, PO Box 440, 00029 HUS, Helsinki, Finland.
Hanna Seppänen *Department of Surgery, University of Helsinki and Helsinki University Hospital, PO Box 440, 00029 HUS, Helsinki, Finland.
Tiina E Lehtimäki *Department of Radiology, HUS Diagnostic Center, University of Helsinki and Helsinki University Hospital, PO Box 340, 00029 HUS, Helsinki, Finland.
Helsinki University Hospital · FIUniversity of Helsinki · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNo previous studies have examined the possible relationship between intraductal papillary mucinous neoplasm (IPMN) and the developmental ductal variations of the pancreas, such as an ansa pancreatica and a meandering main pancreatic duct (MMPD).

methodsThis retrospective cross-sectional study enrolled 214 patients, 108 with IPMN disease and 106 subjects from a community at the tertiary care unit. The main pancreatic duct (MPD) was evaluated in the head of the pancreas by its course, which were non-MMPD: descending, vertical, and sigmoid, or MMPD including loop types, reverse-Z subtypes, and an N-shape, which was identified for the first time in this study. IPMN patients were also evaluated for worrisome features (WF) or high-risk stigmata (HRS), and the extent of IPMN cysts.

resultsAmong IPMN patients, 18.4% had MMPD, which we observed in only 3.0% of the control group (P < 0.001). Patients with MMPD were more likely to belong to the IPMN group compared with non-MMPD patients [odds ratio (OR) 6.4, 95% confidence interval (CI) 2.2-24.9]. Compared with a descending shape MPD, IPMN patients with an N-shaped MPD were more likely to have a cystic mural nodule (OR 5.9, 95% CI 1.02-36.0). The presence of ansa pancreatica associated with more extent IPMN disease (OR 12.8, 95% CI 2.6-127.7).

conclusionsIPMN patients exhibited an MMPD more often than control patients. Ansa pancreatica associated with multiple cysts. Furthermore, an N-shape in IPMN patients associated with cystic mural nodules, suggesting that this shape serves as a risk factor for more severe IPMN.

Indexed as

Adenocarcinoma, MucinousCarcinoma, Pancreatic DuctalCystsPancreatic Intraductal NeoplasmsPancreatic NeoplasmsCross-Sectional StudiesDigestive System AbnormalitiesHumansPancreasPancreatic DuctsRetrospective StudiesAnsa pancreaticaIntraductal papillary mucinous neoplasm (IPMN)Meandering main pancreatic duct (MMPD)MRIWorrisome features

Identifiers

PMID35989322
PMCPMC9394057
OpenAlexW4292527253

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.