ArticleKidney international2022
Kidney disease progression and collider bias in GWAS.
Article in Kidney international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 7 citations in OpenAlex.
- Association of polygenic scores with chronic kidney disease phenotypes in a longitudinal study of older adults.Kidney international · 2023Trial
- Association between ABCG2 transporter functionality and CKD progression: a retrospective cohort study in patients with CKD stage G3.Clinical and experimental nephrology · 2026Article
- From Single-Cell Clusters to Causality: ITCH Engagement for CKD Uncovered by Integrative Analysis of MR and MAGMA.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Article
- An integrative framework for drug target discovery bridging clinical trial and genetic data insights.Journal of translational medicine · 2026Article
Corrections and comments
- Comment on
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
New genome-wide meta-analysis for longitudinal kidney function decline identified several genetic loci related to kidney disease progression. The study illustrated the complexity of modeling longitudinal traits in genome-wide association studies and highlighted the issue of a collider bias that can be introduced when a kidney disease progression phenotype is adjusted for baseline kidney function. Herein, we briefly outline the key findings of this study, their limitations, and implications for future studies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.