Evidence map›Paper›PMID 35988780›Full record

ArticleJournal of controlled release : official journal of the Controlled Release Society2022

Production of paclitaxel-loaded PEG-b-PLA micelles using PEG for drug loading and freeze-drying.

Morteza Rasoulianboroujeni, Lauren Repp, Hye Jin Lee, Glen S Kwon

Open access · greenAbstract read
In one paragraph

Article in Journal of controlled release : official journal of the Controlled Release Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 33 citations in OpenAlex.

  1. High-throughput UPCAnalytical and bioanalytical chemistry · 2026
    Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Crystallization of supersaturated PEG-b-PLA for the production of drug-loaded polymeric micelles.Journal of controlled release : official journal of the Controlled Release Society · 2025
    Article
  7. Article
  8. Nanocarrier-mediated drug delivery systems for spinal cord injury treatment.Frontiers in bioengineering and biotechnology · 2025
    Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Article
  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Morteza RasoulianboroujeniPharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin, 777 Highland Avenue, Madison, WI 53705, United States.
Lauren ReppPharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin, 777 Highland Avenue, Madison, WI 53705, United States.
Hye Jin LeePharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin, 777 Highland Avenue, Madison, WI 53705, United States.
Glen S KwonPharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin, 777 Highland Avenue, Madison, WI 53705, United States. Electronic address: glen.kwon@wisc.edu.
University of Wisconsin–Madison · US

Funding

Oligo(lactic acid)n-Prodrug Nanomedicines for Combination TherapyR01CA257837 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI KWON, GLEN S. · 2021 to 2024
$1.4M
NCI NIH HHS R01 CA257837
6 · The paper itself

Abstract

A new approach named PEG-assist is introduced for the production of drug-loaded polymeric micelles. The method is based on the use of PEG as the non-selective solvent for PEG-b-PLA in the fabrication procedure. Both hydration temperature and PEG molecular weight are shown to have a significant effect on the encapsulation efficiency of PTX in PEG

Indexed as

MicellesPaclitaxelDrug CarriersParticle SizePolyestersPolyethylene GlycolsPolymersSolventsDrug CarriersMicellesmonomethoxypolyethyleneglycol-polylactide block copolymerPaclitaxelPolyestersPolyethylene GlycolsPolymersSolventsDiblock copolymerLiquid-liquid phase separationPaclitaxelPolyethylene glycol-block-polylactic acid (PEG-b-PLA)Polymeric micelleScale up

Identifiers

PMID35988780
PMCPMC9841601
OpenAlexW4293506312

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.