Evidence map›Paper›PMID 35988533›Full record

ArticleJournal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology2022

Males and females have different muscle activity patterns during gait after ACL injury and reconstruction.

Elanna K Arhos, Stephanie Di Stasi, Erin H Hartigan, Lynn Snyder-Mackler

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Article in Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Elanna K ArhosDepartment of Physical Therapy, University of Delaware, Newark, DE, USA; Biomechanics and Movement Science Program, University of Delaware, Newark, DE, USA. Electronic address: earhos@udel.edu.
Stephanie Di StasiDivision of Physical Therapy, School of Health and Rehabilitation Sciences, The Ohio State University, Columbus, OH, USA; Sports Medicine Research Institute, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Erin H HartiganDepartment of Physical Therapy, University of New England, Portland, ME, USA.
Lynn Snyder-MacklerDepartment of Physical Therapy, University of Delaware, Newark, DE, USA; Biomechanics and Movement Science Program, University of Delaware, Newark, DE, USA.

Funding

CAN NEUROMUSCULAR TRAINING ALTER MOVEMENT PATTERNS?R01AR048212 · NIAMS · UNIVERSITY OF DELAWARE · PI SNYDER-MACKLER, LYNN · 2005 to 2015
$3.6M
Can we modify gait asymmetry after ACL reconstruction?F31AR078580 · NIAMS · UNIVERSITY OF DELAWARE · PI ARHOS, ELANNA · 2021 to 2022
$68k
NIAMS NIH HHS F31 AR078580NIAMS NIH HHS R01 AR048212
6 · The paper itself

Abstract

Kinematic and kinetic changes following anterior cruciate ligament (ACL) rupture and reconstruction (ACLR) have been fundamental to the understanding of mechanical disrupted load as it contributes to the development of posttraumatic osteoarthritis. These analyses overlook the potential contribution of muscle activity as it relates to the joint loading environment. Males and females classified as non-copers present with unique knee kinematics and kinetics after ACL injury. The purpose of this study was to perform sex-specific analyses in these individuals to explore muscle activity timing during gait after ACL rupture. Thirty-nine participants (12 females, 27 males) were enrolled. Muscle activity during gait was evaluated before and after pre-operative physical therapy, and six months after ACLR. Surface electromyography data were evaluated to determine timing (e.g., the time the muscle activity begins ('On') and ends ('Off')) for seven muscles: vastus lateralis and medialis (VL, VM), lateral and medial hamstrings (LH, MH), lateral and medial gastrocnemius (LG, MG), and soleus (SOL). General linear models with generalized estimating equations detected the effects of limb and time for muscle activity timing. Males presented with more limb asymmetries before and after pre-operative PT in the VL On (p < 0.001) and Off (p = 0.007), VM On and Off (p < 0.001), and MH off (p < 0.001), but all limb differences resolved by six months post ACLR. Changes in muscle activity in males were pervasive over time in both limbs. Females presented with no interlimb differences pre-operatively, and only involved limb VL off (p = 0.027) and VM off (p = 0.003) and the LH off in both limbs (p < 0.038) changed over time. Our data indicate that inter-limb differences in muscle activity across time points and changes in muscle activity timing over the course of physical therapy were sex specific. Males presented with more inter-limb differences in muscle activity across time points, and females presented with fewer asymmetries before and after pre-operative physical therapy. These data support that sex-specific adaptations should be taken into consideration when assessing biomechanical changes after ACLR.

Indexed as

Anterior Cruciate Ligament InjuriesAnterior Cruciate Ligament ReconstructionBiomechanical PhenomenaFemaleGaitHumansKnee JointMaleMuscle, SkeletalAnterior cruciate ligament (ACL)GaitKneeRehabilitation

Identifiers

PMID35988533
PMCPMC9588796

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