ArticleScientific reports2022
Overexpression of the WAPO-A1 gene increases the number of spikelets per spike in bread wheat.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Characterization and Fine Mapping ofPlants (Basel, Switzerland) · 2026Article
- Advances in gene cloning and functional genomics approaches for wheat (Triticum aestivum L.) improvement.The plant genome · 2026Review
- Identification and validation of a QTL, QSNS.caas-3D.1, for spikelet number per spike in wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Genomics in wheat improvement: Progress and perspectives.The plant genome · 2026Review
- Image-based rachis phenotyping facilitates genetic dissection of spikelet distribution in wheat.Plant physiology · 2026Article
- Integrating meristem initiation and floral fate control: towardFrontiers in plant science · 2026Review
- QSNS.sicau-D12-3B: A novel and major validated QTL governing wheat spikelet number with significant breeding potential.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Molecular dissection of large-spike trait in wheat revealing stable QTLs and REGULATOR OF GRAIN NUMBER1 as targets for yield improvement.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Article
- Historic rewiring of grass flowering time pathways and implications for crop improvement under climate change.The New phytologist · 2025Review
- Breeding potential of Spanish bread wheat landraces: genetic variability in vernalization and photoperiod sensitivity.Frontiers in plant science · 2025Article
- QTL analysis in the Mianmai 902×Taichang 29 RIL population reveals the genetic basis for the high-yield of wheat cultivars Mianmai 902 in terms of spike and plant architecture.BMC plant biology · 2024Article
- A Catalog ofPlants (Basel, Switzerland) · 2024Article
- Delayed development of basal spikelets in wheat explains their increased floret abortion and rudimentary nature.Journal of experimental botany · 2023Article
- Genes Impacting Grain Weight and Number in Wheat (Plants (Basel, Switzerland) · 2022Review
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Authors and funding
17 authors.
Funding
Abstract
Two homoeologous QTLs for number of spikelets per spike (SPS) were mapped on chromosomes 7AL and 7BL using two wheat MAGIC populations. Sets of lines contrasting for the QTL on 7AL were developed which allowed for the validation and fine mapping of the 7AL QTL and for the identification of a previously described candidate gene, WHEAT ORTHOLOG OF APO1 (WAPO1). Using transgenic overexpression in both a low and a high SPS line, we provide a functional validation for the role of this gene in determining SPS also in hexaploid wheat. We show that the expression levels of this gene positively correlate with SPS in multiple MAGIC founder lines under field conditions as well as in transgenic lines grown in the greenhouse. This work highlights the potential use of WAPO1 in hexaploid wheat for further yield increases. The impact of WAPO1 and SPS on yield depends on other genetic and environmental factors, hence, will require a finely balanced expression level to avoid the development of detrimental pleiotropic phenotypes.
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