ArticleJournal of cardiothoracic surgery2022
The diagnostic and prognostic value of D-dimer in different types of aortic dissection.
Article in Journal of cardiothoracic surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed.
- Machine learning-based prediction of postoperative continuous renal replacement therapy initiation after open thoracoabdominal aortic repair.BMC nephrology · 2026Article
- A D-dimer and ADAMTS8 based multi-marker score for the diagnosis of acute aortic dissection.Scientific reports · 2026Article
- Development and validation of identification models for aortic dissection and non-ST-segment elevation acute coronary syndrome in the emergency department.Scientific reports · 2025Article
- Relationship between perioperative plasma neutrophil gelatinase-associated lipocalin level and acute kidney injury after acute type A aortic dissection.Journal of thoracic disease · 2025Article
- Interpretable prognostic modeling for long-term survival of Type A aortic dissection patients using support vector machine algorithm.European journal of medical research · 2025Article
- Prognostic prediction of long-term survival in patients with type A aortic dissection undergoing surgical repair: development of a novel prognostic index.BMC cardiovascular disorders · 2025Article
- Review
- Clinical significance of elevated D-dimer in emergency department patients: a retrospective single-center analysis.International journal of emergency medicine · 2024Article
- Predictive value of preoperative platelet count and D-dimer levels for spinal cord injury following acute type a aortic dissection.Journal of cardiothoracic surgery · 2024Article
- Development of a machine learning-based model to predict major adverse events after surgery for type A aortic dissection complicated by malnutrition.Frontiers in nutrition · 2024Article
- D-dimer as a Rule-Out for Aortic Dissection.Cureus · 2023Article
- Surgical timing of endoluminal repair of Stanford type B aortic coarctation and relationship to prognosis: a single-center retrospective cohort study.Journal of thoracic disease · 2023Article
- Relationship between preoperative lymphocyte to monocyte ratio and surgery outcome in type A aortic dissection.Frontiers in surgery · 2022Article
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6 authors.
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Abstract
objectiveTo evaluate the serum D-dimer level and its diagnostic and prognostic predictive value in patients with different types of aortic dissection.
methodsEighty-four aortic dissection patients who were diagnosed clinically in our hospital from January 2017 to January 2021 were selected for the study. All patients were divided into Stanford type A (39 cases) and Stanford type B (45 cases) groups. The serum D-dimer level was detected at 1 h, 6 h, 12 h, 24 h, and 72 h after admission to the hospital, and its expression level with different types of aortic dissection was analyzed. The relationship between D-dimer and the prognosis of patients was also analyzed.
resultsThe serum D-dimer levels of patients in group A were significantly higher than those in group B at 6 h, 12 h, 24 h, and 72 h after admission, and the differences were statistically significant. In group A, 16 patients died, and 23 patients survived, while in group B, 18 patients died, and 27 patients survived. The serum D-dimer level of the dead and surviving patients in group A was significantly higher than that of group B, and the serum D-dimer level of dead patients in groups A and B was significantly higher than that of surviving patients. For diagnostic value, the AUC was 0.89, sensitivity was 76.92%, specificity was 90.00% in group A, and the AUC was 0.82, sensitivity was 71.11%, and specificity was 85.00% in group B. For the prognostic predicted value, the AUC was 0.74 in group A, while the AUC was 0.69 in group B.
conclusionsD-dimer has different serum levels in different types of aortic dissection patients, with higher levels in Stanford A. Serum D-dimer levels may be used as a better biomarker to diagnose the two types of aortic dissection and play an important role in patient prognostic prediction, especially Stanford type A.
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