Evidence map›Paper›PMID 35987699›Full record

ArticleStem cell research & therapy2022

Towards establishing human body-on-a-chip systems.

Zhong Alan Li, Rocky S Tuan

Abstract readLetterComment
In one paragraph

Article in Stem cell research & therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Review
  2. Review
  3. European heart journal open · 2025
    Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Targeted Cancer Therapy-on-A-Chip.Advanced healthcare materials · 2024
    Review
  11. Review
  12. Review
  13. In Vitro Models for Investigating Intestinal Host-Pathogen Interactions.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Review
  14. Review
  15. Review
  16. Review
  17. Validation of an on-chip p16Scientific reports · 2023
    Article
  18. Review
  19. Review
  20. Journal of tissue engineering
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Zhong Alan LiDepartment of Biomedical Engineering, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China.
Rocky S TuanInstitute for Tissue Engineering and Regenerative Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China. tuanr@cuhk.edu.hk.ORCID 0000-0001-6067-6705

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Body-on-a-chip (BoC) platforms are established from multiple organs-on-chips (OoCs) to recapitulate the interactions between different tissues. Recently, Vunjak-Novakovic and colleagues reported the creation of a BoC system comprising four fluidically linked OoCs. Herein, the major innovations in their BoC system are discussed, followed by our future perspectives on enhancing the physiological relevance and scalability of BoCs for applications in studying disease mechanisms, testing potential therapeutics, and developing personalized medicine.

Indexed as

Human BodyLab-On-A-Chip DevicesHumansPrecision MedicineBody-on-a-chipDisease modellingDrug testingMicrofluidic deviceOrgan-on-a-chipPatient-on-a-chipPrecision medicineStem cell

Identifiers

PMID35987699
PMCPMC9392934

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.