ArticleItalian journal of pediatrics2022
Analysis of the risk factors and clinical features of Mycoplasma pneumoniae pneumonia with embolism in children: a retrospective study.
Article in Italian journal of pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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22 citing papers in PubMed, 30 citations in OpenAlex.
- Neutrophils promote endothelial cell activation in pediatric Mycoplasma pneumoniae pneumonia.JCI insight · 2026Article
- Application of Clinical Indicators in the Early Prediction of RefractoryClinical pediatrics · 2026Article
- Qingxuan Zhike Granules Modulate Gut Dysbiosis and Enhance Intestinal Repair in MurineJournal of microbiology and biotechnology · 2026Article
- Management of pulmonary thromboembolism in children: an evidence-based expert consensus.World journal of pediatrics : WJP · 2026Article
- Advances in treatment and prevention of pulmonary thromboembolism associated with Mycoplasma pneumoniae pneumonia in children.Pediatric research · 2026Review
- Factors associated with pulmonary embolism in children with refractoryFrontiers in pediatrics · 2026Article
- Clinical characteristics, predictive factors, and therapeutic outcomes of mycoplasma pneumoniae pneumonia with pleural effusion in children: a retrospective cohort study.Frontiers in pediatrics · 2026Article
- Serum expression of ESM-1 and Syndecan-1 and its relationship with disease severity in children with Mycoplasma pneumoniae pneumonia.Italian journal of pediatrics · 2025Observational
- Interventional therapy for a case of Mycoplasma pneumoniae pneumonia complicated by upper extremity arterial embolism in a child: a case report.Thrombosis journal · 2025Article
- Bronchoalveolar lavage cytokine profile and clinical features as risk predictors of plastic bronchitis in children with Mycoplasma pneumoniae pneumonia.Italian journal of pediatrics · 2025Article
- Prediction model for severe mycoplasma pneumoniae pneumonia and analysis of macrolide-resistance in children: a case-control study.Italian journal of pediatrics · 2025Article
- Low-dose and low-contrast computed tomography pulmonary angiography in pediatric with pulmonary embolism: a prospective study.BMC medical imaging · 2025Article
- Case Report: RefractoryFrontiers in pediatrics · 2025Article
- Successful rivaroxaban and doxycycline therapy forFrontiers in pediatrics · 2025Article
- Pulmonary thromboembolism due to Mycoplasma pneumoniae in children: a case report and literature review.BMC pediatrics · 2024Review
- Clinical characteristics and risk factors of pulmonary embolism with Mycoplasma pneumoniae pneumonia in children.Scientific reports · 2024Article
- The chicken or the egg?European heart journal. Case reports · 2024Article
- Establishment of a Mouse Model ofMicroorganisms · 2024Article
- [Risk factors for embolism in children with refractoryZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2024Article
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7 authors at 3 institutions in 1 country.
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Abstract
backgroundMycoplasma pneumoniae pneumonia (MPP) is a prevalent disease in community-acquired pneumonia among children. However, in addition to respiratory manifestations, it may also develop extra-pulmonary complications. Embolism is one of the uncommon extra-respiratory manifestations prone to severe sequelae and even death. This study aims to analyze the clinical features of MPP with embolism in children, and explore the associated risk factors of embolism in MPP patients.
methodsA retrospective case-control analysis was performed on 48 children with MPP admitted to our hospital wards between January 2010 and December 2021. Embolism group comprised children with embolism by CTA or MRA results, whereas the non-embolism group comprised children with clinical suspicion of embolism but negative diagnostic imaging support. The clinical features, laboratory findings and imaging were analyzed to explore the risk factors for embolism in children with MPP.
resultsA total of 48 children with MPP were enrolled in the study (16 cases and 32 controls). In the embolism group, 10 patients (62.5%) had pulmonary embolism, 3 patients (18.75%) presented ventricle embolism, 2 patients (12.5%) presented cerebral and carotid artery embolism, one patient (6.25%) had a cerebral embolism, limb, and spleen, respectively. The univariate analysis revealed the maximum body temperature (Tmax), CRP, D-dimer (closest to CTA/MRA), the percentage of neutrophils (N%), pulmonary consolidation (⩾ 2/3 lobe), pleural effusion and atelectasis have significant differences between the embolism group and non-embolism group (P < 0.05). Multivariate logistic regression analysis showed that D-dimer (closest to CTA/MRA) > 3.55 mg/L [OR = 1.255 (95% CI: 1.025-1.537), P < 0.05], pulmonary consolidation (⩾ 2/3 lobe) [OR = 8.050 (95% CI: 1.341-48.327), P < 0.05], and pleural effusion [OR = 25.321 (95% CI: 2.738-234.205), P < 0.01] were independent risk factors for embolism in children with MPP.
conclusionIn conclusion, MPP with embolism patients have more D-dimer values and severe radiologic manifestations.
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