Evidence map›Paper›PMID 35987625›Full record

Trial reportMalaria journal2022

Costs of treating childhood malaria, diarrhoea and pneumonia in rural Mozambique and Uganda.

Neha Batura, Frida Kasteng, Juliao Condoane, Benson Bagorogosa, Ana Cristina Castel-Branco, Edmound Kertho, Karin Källander, Seyi Soremekun, Raghu Lingam, Anna Vassall and 1 more

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Malaria journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01972321 (Integrated Community Case Management of Common Childhood Diseases), which is not on this map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01972321 nacompletednot on this map

Integrated Community Case Management of Common Childhood Diseases: Mozambique and Uganda

TypeinterventionalSponsorMalaria ConsortiumRan2013 to 2015Enrolled2,289ConditionsMalaria, Pneumonia, DiarrhoeaArmsTechnology supported supervision, Community supported supervision, Integrated community case management
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. Article
  7. Observational
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Neha BaturaInstitute for Global Health, University College London, 30 Guilford Street, London, WC1 1EH, UK. n.batura@ucl.ac.uk.ORCID http://orcid.org/0000-0002-8175-8125
Frida KastengDepartment of Global Public Health, Karolinska Institutet, K9, 171 77, Stockholm, Sweden.
Juliao CondoaneMalaria Consortium, Rua Joseph Ki-Zerbo, 191 Sommerschield, Maputo, Mozambique.
Benson BagorogosaMalaria Consortium, Plot 25 Upper Naguru East Road, P.O.Box 8045, Kampala, Uganda.
Ana Cristina Castel-BrancoMalaria Consortium, Rua Joseph Ki-Zerbo, 191 Sommerschield, Maputo, Mozambique.
Edmound KerthoMalaria Consortium, Plot 25 Upper Naguru East Road, P.O.Box 8045, Kampala, Uganda.
Karin KällanderDepartment of Global Public Health, Karolinska Institutet, K9, 171 77, Stockholm, Sweden.
Seyi SoremekunDepartment of Clinical Research London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK.
Raghu LingamDepartment of Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK.
Anna VassallDepartment of Global Health and Development, London School of Hygiene and Tropical Medicine, 15-17 Tavistock Place, London, WC1H 9SH, UK.
inSCALE study group

Funding

Bill and Melinda Gates Foundation OPP1002407
6 · The paper itself

Abstract

backgroundGlobally, nearly half of all deaths among children under the age of 5 years can be attributed to malaria, diarrhoea, and pneumonia. A significant proportion of these deaths occur in sub-Saharan Africa. Despite several programmes implemented in sub-Saharan Africa, the burden of these illnesses remains persistently high. To mobilise resources for such programmes it is necessary to evaluate their costs, costs-effectiveness, and affordability. This study aimed to estimate the provider costs of treating malaria, diarrhoea, and pneumonia among children under the age of 5 years in routine settings at the health facility level in rural Uganda and Mozambique.

methodsService and cost data was collected from health facilities in midwestern Uganda and Inhambane province, Mozambique from private and public health facilities. Financial and economic costs of providing care for childhood illnesses were investigated from the provider perspective by combining a top-down and bottom-up approach to estimate unit costs and annual total costs for different types of visits for these illnesses. All costs were collected in Ugandan shillings and Mozambican meticais. Costs are presented in 2021 US dollars.

resultsIn Uganda, the highest number of outpatient visits were for children with uncomplicated malaria and of inpatient admissions were for respiratory infections, including pneumonia. The highest unit cost for outpatient visits was for pneumonia (and other respiratory infections) and ranged from $0.5 to 2.3, while the highest unit cost for inpatient admissions was for malaria ($19.6). In Mozambique, the highest numbers of outpatient and inpatient admissions visits were for malaria. The highest unit costs were for malaria too, ranging from $2.5 to 4.2 for outpatient visits and $3.8 for inpatient admissions. The greatest contributors to costs in both countries were drugs and diagnostics, followed by staff.

conclusionsThe findings highlighted the intensive resource use in the treatment of malaria and pneumonia for outpatient and inpatient cases, particularly at higher level health facilities. Timely treatment to prevent severe complications associated with these illnesses can also avoid high costs to health providers, and households.

trial registrationClinicalTrials.gov, identifier: NCT01972321.

Indexed as

DiarrheaHealth Care CostsMalariaPneumoniaChild, PreschoolHumansInfantMozambiqueRural Health ServicesUgandaCostsDiarrhoeaMalariaMozambiquePneumoniaUganda

Identifiers

PMID35987625
PMCPMC9392282

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.