Evidence map›Paper›PMID 35986928›Full record

ArticleBritish journal of clinical pharmacology2023

Hospital pharmacists' opinions on a risk prediction tool for medication-related harm in older people.

Ahmed Hussain, Khalid Ali, J Graham Davies, Jennifer M Stevenson, Samantha Lippett, Mairead O'Malley, Nikesh Parekh, Chakravarthi Rajkumar

Open access · hybridAbstract read
In one paragraph

Article in British journal of clinical pharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Ahmed HussainBarts Health NHS Trust, London, UK.ORCID 0000-0003-2246-1791
Khalid AliDepartment of Elderly Medicine, University Hospitals Sussex NHS Foundation Trust, Sussex, UK.
J Graham DaviesInstitute of Pharmaceutical Science, King's College London, London, UK.
Jennifer M StevensonInstitute of Pharmaceutical Science, King's College London, London, UK.
Samantha LippettPharmacy Department, University Hospitals Sussex NHS Foundation Trust, Sussex, UK.
Mairead O'MalleyPharmacy Department, University Hospitals Sussex NHS Foundation Trust, Sussex, UK.
Nikesh ParekhDepartment of Elderly Medicine, University Hospitals Sussex NHS Foundation Trust, Sussex, UK.
Chakravarthi RajkumarDepartment of Elderly Medicine, University Hospitals Sussex NHS Foundation Trust, Sussex, UK.
Brighton and Sussex Medical School · GBKing's College London · GBUniversity Hospitals Sussex NHS Foundation Trust · GBBarts Health NHS Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimOlder adults are particularly affected by medication-related harm (MRH) during transitions of care. There are no clinical tools predicting those at highest risk of MRH post hospital discharge. The PRIME study (prospective study to develop a model to stratify the risk of MRH in hospitalized patients) developed and internally validated a risk-prediction tool (RPT) that provides a percentage score of MRH in adults over 65 in the 8 weeks following hospital discharge. This qualitative study aimed to explore the views of hospital pharmacists around enablers and barriers to clinical implementation of the PRIME-RPT.

methodsTen hospital pharmacists: (band 6, n = 3; band 7, n = 2; band 8, n = 5) participated in semistructured interviews at the Royal Sussex County Hospital (Brighton, UK). The pharmacists were presented with five case-vignettes each with a calculated PRIME-RPT score to help guide discussion. Case-vignettes were designed to be representative of common clinical encounters. Data were thematically analysed using a "framework" approach.

resultsSeven themes emerged in relation to the PRIME-RPT: (1) providing a medicine-prioritisation aide; (2) acting as a deprescribing alert; (3) facilitating a holistic review of patient medication management; (4) simplifying communication of MRH to patients and the multidisciplinary team; (5) streamlining community follow-up and integration of risk discussion into clinical practice; (6) identifying barriers for the RPTs integration in clinical practice; and (7) acknowledging its limitations.

conclusionHospital pharmacists found the PRIME-RPT beneficial in identifying older patients at high risk of MRH following hospital discharge, facilitating prioritising interventions to those at highest risk while still acknowledging its limitations.

Indexed as

Patient DischargePharmacistsAgedHospitalsHumansProspective StudiesQualitative Researchfrailtymedicinesolder adultspolypharmacyrisk assessmentrisk prediction

Identifiers

PMID35986928
PMCPMC10087672
OpenAlexW4292450722

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.