Evidence map›Paper›PMID 35986809›Full record

ArticleJournal of assisted reproduction and genetics2022

Gamete and embryo donation for research: what might shape the willingness to donate among gamete donors and recipients?

Sandra Pinto da Silva, Cláudia de Freitas, Milton Severo, Susana Silva

Open access · bronzeAbstract read
In one paragraph

Article in Journal of assisted reproduction and genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Sandra Pinto da SilvaEPIUnit - Instituto de Saúde Pública, Universidade do Porto, Rua das Taipas nº135, 4050‑600, Porto, Portugal. pintodasilva.sps@gmail.com.ORCID http://orcid.org/0000-0003-4718-5957
Cláudia de FreitasEPIUnit - Instituto de Saúde Pública, Universidade do Porto, Rua das Taipas nº135, 4050‑600, Porto, Portugal.ORCID http://orcid.org/0000-0002-1828-8642
Milton SeveroEPIUnit - Instituto de Saúde Pública, Universidade do Porto, Rua das Taipas nº135, 4050‑600, Porto, Portugal.ORCID http://orcid.org/0000-0002-5787-4871
Susana SilvaDepartment of Sociology, Institute of Social Sciences, University of Minho, Campus de Gualtar, 4710-​057, Braga, Portugal.ORCID http://orcid.org/0000-0002-1335-8648
Universidade do Porto · PTCentre for Research in Anthropology · PT

Funding

European Regional Development Fund citizenship in gamete donation);POCI-01-0145-FEDER-006862European Regional Development Fund POCI-01-0145-FEDER-016762European Regional Development Fund Ref. FCT PTDC/IVC-ESCT/6294/2014 (ENGAgED - BionetworkingEuropean Regional Development Fund Ref. FCT UIDB/04750/2020 (Unidade de Investigação em Epidemiologia - Instituto de Saúde Pública da Universidade do Porto - EPIUnit); SFRH/BD/122603/2016 (Sandra Pinto da Silva); DL57/2016/CP1336/CT0001 (Cláudia de Freitas); IF/01674/2015 (Susana Silva)European Social Fund citizenship in gamete donation);POCI-01-0145-FEDER-006862European Social Fund POCI-01-0145-FEDER-016762European Social Fund Ref. FCT PTDC/IVC-ESCT/6294/2014 (ENGAgED - BionetworkingEuropean Social Fund Ref. FCT UIDB/04750/2020 (Unidade de Investigação em Epidemiologia - Instituto de Saúde Pública da Universidade do Porto - EPIUnit); SFRH/BD/122603/2016 (Sandra Pinto da Silva); DL57/2016/CP1336/CT0001 (Cláudia de Freitas); IF/01674/2015 (Susana Silva)Fundação para a Ciência e a Tecnologia citizenship in gamete donation);POCI-01-0145-FEDER-006862Fundação para a Ciência e a Tecnologia POCI-01-0145-FEDER-016762Fundação para a Ciência e a Tecnologia Ref. FCT PTDC/IVC-ESCT/6294/2014 (ENGAgED - BionetworkingFundação para a Ciência e a Tecnologia Ref. FCT UIDB/04750/2020 (Unidade de Investigação em Epidemiologia - Instituto de Saúde Pública da Universidade do Porto - EPIUnit); SFRH/BD/122603/2016 (Sandra Pinto da Silva); DL57/2016/CP1336/CT0001 (Cláudia de Freitas); IF/01674/2015 (Susana Silva)
6 · The paper itself

Abstract

purposeResearch using gametes and embryos donated by reproductive and third-party donors contributed to substantial, albeit contentious achievements. The views of gamete donors and recipients on donation for research and the underpinning role of attitudes towards research have been seldom explored and are yet to be incorporated into ethical, legal, and regulatory landscapes. From a cultural standpoint, this study adapts and explores psychometric properties of the Portuguese version of the Research Attitudes Questionnaire (RAQ), and analyzes the willingness of gamete donors and recipients to donate gametes and embryos for research and its association with sociodemographic, reproductive characteristics, and attitudes towards research.

methodsBetween July 2017 and June 2018, 71 donors and 165 recipients completed a self-administered questionnaire at the Portuguese Public Bank of Gametes. Willingness to donate and attitudes towards research were measured with a 5-point Likert scale. RAQ psychometric characteristics were explored.

resultsTwo RAQ components were identified: "trustworthiness of research" and "critical perspective". Most participants were willing to donate gametes and embryos: donors more willing to donate gametes and male recipients more willing to donate gametes and embryos. Higher RAQ scores, indicating a more positive attitude towards research, were observed on the component "trustworthiness of research" among those willing to donate gametes and embryos and on the component "critical perspective" among those willing to donate embryos.

conclusionThese findings help foster inclusivity, diversity, and responsiveness of research and call for upstream engagement of male and female gamete donors and recipients, promoting a trustworthy, anticipatory, democratic, and people-centered approach to policies, regulations, and practices in human gamete and embryo research.

Indexed as

Embryo DispositionEmbryo ResearchFemaleGerm CellsHumansMaleOocyte DonationTissue DonorsAssisted reproductive technologiesAttitudesEmbryo dispositionEmbryo researchGamete donationTrust

Identifiers

PMID35986809
PMCPMC9475016
OpenAlexW4294071808

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.