ArticleWorld journal of urology2023
Ultrasound-based "CEUS-Bosniak"classification for cystic renal lesions: an 8-year clinical experience.
Article in World journal of urology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed, 25 citations in OpenAlex.
- The Efficacy and Safety of Dehydrated Alcohol Versus Lauromacrogol for Sclerotherapy of Simple Renal Cysts: A Retrospective Comparison Study.Health science reports · 2026Article
- CEUS in Atypical Renal Cystic Masses: How, When and Why.Medicina (Kaunas, Lithuania) · 2026Review
- ChatGPT-4V prompt: A tool to enhance junior radiologists' diagnostic capabilities in cystic renal masses to senior-level accuracy.Computational and structural biotechnology journal · 2026Article
- The value of contrast-enhanced ultrasound in the follow-up of Bosniak IIF cystic renal lesions.BMC medical imaging · 2025Article
- Qualitative and Quantitative Analysis of Contrast-Enhanced Ultrasound in the Characterization of Kidney Cancer Subtypes.Diagnostics (Basel, Switzerland) · 2025Article
- Clinical value of contrast-enhanced ultrasound combined with quantitative analysis in Bosniak ≥ II cystic renal masses.Abdominal radiology (New York) · 2025Article
- Contrast-enhanced ultrasound of renal masses in the pre-transplant setting: literature review with case highlights.Abdominal radiology (New York) · 2024Review
- Contrast-enhanced US Bosniak Classification: intra- and inter-rater agreement, confounding features, and diagnostic performance.Insights into imaging · 2024Article
- Advanced ultrasound methods to improve chronic kidney disease diagnosis.Npj imaging · 2024Review
- Contrast-Enhanced Ultrasound in the Diagnosis of Solid Renal Lesions.Journal of clinical medicine · 2024Review
- Contrast-enhanced ultrasound for differentiating benign from malignant focal solid renal lesions in pediatric patients.Scientific reports · 2024Article
- CEUS Bosniak Classification-Time for Differentiation and Change in Renal Cyst Surveillance.Cancers · 2023Review
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Authors and funding
16 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeRenal cysts comprise benign and malignant entities. Risk assessment profits from CT/MRI imaging using the Bosniak classification. While Bosniak-IIF, -III, and -IV cover complex cyst variants, Bosniak-IIF and -III stand out due to notorious overestimation. Contrast-enhanced ultrasound (CEUS) is promising to overcome this deficit but warrants standardization. This study addresses the benefits of a combined CEUS and CT/MRI evaluation of renal cysts. The study provides a realistic account of kidney tumor boards' intricacies in trying to validate renal cysts.
methods247 patients were examined over 8 years. CEUS lesions were graded according to CEUS-Bosniak (IIF, III, IV). 55 lesions were resected, CEUS-Bosniak- and CT/MRI-Bosniak-classification were correlated with histopathological diagnosis. Interobserver agreement between the classifications was evaluated statistically. 105 lesions were followed by ultrasound, and change in CEUS-Bosniak-types and lesion size were documented.
results146 patients (156 lesions) were included. CEUS classified 67 lesions as CEUS-Bosniak-IIF, 44 as CEUS-Bosniak-III, and 45 as CEUS-Bosniak-IV. Histopathology of 55 resected lesions revealed benign cysts in all CEUS-Bosniak-IIF lesions (2/2), 40% of CEUS-Bosniak-III and 8% of CEUS-Bosniak-IV, whereas malignancy was uncovered in 60% of CEUS-Bosniak-III and 92% of CEUS-Bosniak-IV. Overall, CEUS-Bosniak-types matched CT/MRI-Bosniak types in 58% (fair agreement, κ = 0.28). CEUS-Bosniak resulted in higher stages than CT/MRI-Bosniak (40%). Ultrasound follow-up of 105 lesions detected no relevant differences between CEUS-Bosniak-types concerning cysts size. 99% of lesions showed the same CEUS-Bosniak-type.
conclusionThe CEUS-Bosniak classification is an essential tool in clinical practice to differentiate and monitor renal cystic lesions and empowers diagnostic work-up and patient care.
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