ArticleTransfusion2022
Red blood cell alloimmunization and other transfusion-related complications in patients with transfusion-dependent thalassemia: A multi-center study in Thailand.
Article in Transfusion, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.
- [Guideline for transfusion management in Chinese children with transfusion-dependent thalassemia (2025)].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2025Guideline
- Red cell alloantibodies in 71,525 Malaysian blood donations: Predominance of anti-Mia reflects GP.Mur-associated antigenic diversity.Vox sanguinis · 2026Article
- Optimization of the antibody identification interval in a high-volume transfusion centre.Vox sanguinis · 2026Article
- Disease-related complications and risk factors in hemoglobin H disease in a Thai multicenter registry.Scientific reports · 2026Article
- Luspatercept in Transfusion-Dependent Thalassemia With Red Blood Cell Antibodies: A Case Series.EJHaem · 2026Article
- Cost-effectiveness and budget impact of Luspatercept in Thai adults with transfusion-dependent beta-thalassaemia: a multi-state Markov model based on national claims data.Journal of pharmaceutical policy and practice · 2026Article
- Investigation of alloimmunization in beta-thalassemia major patients: a cross-sectional study.Annals of medicine and surgery (2012) · 2025Article
- Association between HLA-DRB1*04, HLA-DQB1*03, and HLA-DQB1*06 with alloimmunization in transfusion-dependent patients with thalassemia: the first case-control study in Iran.Annals of hematology · 2025Article
- Association between HLA-DRB1*04, HLA-DQB1*03, and HLA-DQB1*06 with alloimmunization in transfusion-dependent patients with thalassemia: the first case-control study in Iran.Annals of hematology · 2025Article
- Prevalence of Alloimmunization Events in Thalassemia Patients With Repeated Transfusions in the Rhesus Blood Group System: A Systematic Review and Meta Analysis.Journal of clinical medicine research · 2025Article
- Multiplex-PCR technique to predict polymorphic antigens - M, N, S and s - and associations between their alleles and MiScientific reports · 2025Article
- Platelet alloimmunization in transfusion-dependent thalassemia patients from Southern China (2014-2023).Frontiers in immunology · 2025Article
- Risk Stratification for Autoimmune Hemolytic Anemia in Children With Pediatric Transfusion-Dependent Thalassemia.Cureus · 2024Article
- Characterization of pediatric transfusion-dependent thalassemia patients in a large academic center.Journal of clinical laboratory analysis · 2023Article
Corrections and comments
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Authors and funding
14 authors at 8 institutions in 1 country.
Funding
Abstract
backgroundThalassemia is a common genetic disease in Southeast Asia. Red blood cell (RBC) transfusion is an essential treatment for severe forms of thalassemia. We performed a study to demonstrate RBC alloimmunization and other transfusion-related complications in patients with transfusion-dependent thalassemia (TDT). STUDY DESIGN AND
methodsA multi-center web-based registry of TDT was conducted in eight medical centers across Thailand. Thalassemia information, transfusion therapy, and transfusion-related complications were collected. Factors associated with each complication were demonstrated using the logistic regression analysis.
resultsOf 1000 patients recruited for the study, 449 were males (44.9%). The mean age was 23.9 ± 15.4 years. The majority of patients, 738 (73.8%) had hemoglobin E/beta-thalassemia. In the study, 421 transfusion-related complications were reported from 357 patients (35.7%). Alloimmunization was the most common complication which was found in 156 patients (15.6%) with 284 positive antibody tests. The most frequent antibodies against RBC were anti-E (80/284, 28.2%) followed by anti-Mi
conclusionsTransfusion-related complications, especially alloimmunization, were common among Thai patients with TDT. Extended RBC antigen-matching for the Rh system and Mi
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